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[良性食管狭窄的治疗:20年后的重新评估]

[Treatment of benign esophageal stenosis: re-evaluation after 20 years].

作者信息

Chiocca J C, Graciela B, Stupnik S, Mazure P A

机构信息

Servicio de Gastroenterología, Hospital Nacional Profesor Alejandro Posadas, Buenos Aires, Argentina.

出版信息

Acta Gastroenterol Latinoam. 1990;20(4):225-9.

PMID:2135569
Abstract

In 1972 we described a method for dilatation of esophageal stenosis. The purpose of this paper is to report the results obtained between 1970 and 1989, the patients were studied by X-Rays, "calibration" of the stenosis, endoscopy, biopsy, cytology, gastric analysis and esophageal motility. One hundred and seven patients were treated (mean 60.5 years, M/F 3.9/1). The most frequent etiology was reflux esophagitis (80.3%). Hiatus hernia was present in 84.9%. The stenosis was in the lower third of the esophagus in 92.5%. The BAO was mean: 3.6 mEq/h, and the MAO mean 16.4 mEq/h with a hypersecretion pattern in 33.1% of the cases. Cytology was negative for malignancy in 100%. Biopsy showed esophagitis in 86.9%, Barrett's epithelium in 12.1%, normal tissue in 6.5% and insufficient material in 1.8%. Endoscopy showed 98.1% of grade IV esophagitis. Esophageal motility showed a HPZ of mean 6.5 mmHg. and varying degrees of aperistalsis in 24.3% of the patients. The total number of dilatations was 555 (mean 5.1/pt). The "calibration" of the stenosis previous to the dilatation was mean 8.6 mm, and post dilatation mean 15.6 mm. The result of the procedure was good in 92.5%, regular in 2.8% and bad in 4.6%. The morbidity was 0.9% and the mortality 0.1%. There was relapse of the stenosis in 42% of the cases, the follow-up was mean 3.2 years. Twenty nine patients were submitted to surgery due to failure of the procedure with 68.1% of good results, morbidity of 9% and mortality of 9%. We conclude that this dilatation procedure offers excellent results with a very low morbi-mortality.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1972年我们描述了一种食管狭窄扩张术。本文旨在报告1970年至1989年间所取得的结果,对患者进行了X线检查、狭窄“校准”、内镜检查、活检、细胞学检查、胃液分析及食管动力检查。共治疗了107例患者(平均年龄60.5岁,男女比例为3.9∶1)。最常见的病因是反流性食管炎(80.3%)。84.9%的患者存在食管裂孔疝。92.5%的狭窄位于食管下三分之一处。基础胃酸分泌量平均为3.6 mEq/h,最大胃酸分泌量平均为16.4 mEq/h,33.1%的病例呈胃酸分泌过多模式。细胞学检查恶性肿瘤均为阴性。活检显示食管炎占86.9%,巴雷特食管上皮占12.1%,正常组织占6.5%,取材不足占1.8%。内镜检查显示98.1%为IV级食管炎。食管动力检查显示高压区平均为6.5 mmHg,24.3%的患者有不同程度的蠕动消失。扩张总数为555次(平均每例5.1次)。扩张前狭窄“校准”平均为8.6 mm,扩张后平均为15.6 mm。手术效果良好的占92.5%,一般的占2.8%,差的占4.6%。发病率为0.9%,死亡率为0.1%。42%的病例出现狭窄复发,平均随访3.2年。29例患者因手术失败接受了手术,手术效果良好的占68.1%,发病率为9%,死亡率为9%。我们得出结论,这种扩张术效果极佳,病死率和发病率极低。(摘要截选至250字)

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