Department of Renal Medicine and Transplantation, St George's Hospital, London, UK.
Department of Cellular Pathology, St George's Hospital, London, UK.
Kidney Int. 2011 Mar;79(6):579-581. doi: 10.1038/ki.2010.495.
Classical renal tuberculosis is a well-known cause of urinary tract scarring and calcification, and sometimes renal dysfunction. In the past two decades there have been reports, particularly from the United Kingdom among immigrants from the Indian subcontinent, of a more insidiously progressive form of renal disease. Ultrasound shows small smooth kidneys, and histology reveals tubulointerstitial nephritis including granulomas but not acid-fast bacilli. Evidence is mounting that the underlying cause may be tuberculosis, but the mechanism remains obscure.
经典型肾结核是导致尿路瘢痕和钙化，有时还会导致肾功能障碍的一个众所周知的原因。在过去二十年中，特别是在英国，来自印度次大陆的移民中，出现了一种更为隐匿性的进行性肾脏疾病。超声显示肾脏较小且光滑，组织学显示存在包括肉芽肿但没有抗酸杆菌的肾小管间质性肾炎。越来越多的证据表明，潜在病因可能是结核病，但机制仍不清楚。
