Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Chem Commun (Camb). 2011 Apr 14;47(14):4222-4. doi: 10.1039/c0cc04917d. Epub 2011 Feb 28.
The fluorescence of a new aminocyanonaphthalene exhibits exquisite sensitivity to its environment and responds to a solvent change from water to hexane with greater than a 100-fold increase in intensity and 100 nm shift in λ(max.em). These properties should support many applications including the detection of abasic sites within duplex DNA as illustrated below.
一种新型的氨基氰萘荧光染料对其环境具有极高的灵敏度，当溶剂从水变为己烷时，其荧光强度增加超过 100 倍，最大发射波长发生 100nm 的位移。这些特性应该支持许多应用，包括检测双链 DNA 中的无碱基位点，如下所示。
