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老年慢性血液透析患者的住院情况。

Hospital admissions in elderly patients on chronic hemodialysis.

机构信息

Medicine Service, Raymond G Murphy Veterans Affairs Medical Center and Department of Medicine, University of New Mexico School of Medicine, 1501 San Pedro, SE, Albuquerque, New Mexico 87108, USA.

出版信息

Int Urol Nephrol. 2011 Dec;43(4):1229-36. doi: 10.1007/s11255-011-9913-1. Epub 2011 Mar 2.

Abstract

BACKGROUND

The purpose of this study was to determine whether number of hospital admissions per patient per year (n/[pt-yr]) and hospital days per patient per year (d/[pt-yr]) differ between elderly and younger patients on chronic hemodialysis (HD).

PATIENTS AND METHODS

In a retrospective cohort analysis of incident HD patients in one dialysis unit over 15 years, we compared 166 HD patients older than 70 years (77.1 ± 4.7 yrs) at the onset of HD (group A) and 216 patients younger than 70 years both at onset (57.1 ± 7.6 yrs) and at the end of the HD period (group B). Eighty (48.2%) of group A and 141 (65.3%) patients of group B had diabetes mellitus.

RESULTS

No differences were noted in the overall hospitalization rate, presented as mean, {95% Confidence interval} (group A 2.40 {2.04-2.75}, group B 2.03 {1.89-2.16} n[pt-yr]) and days/[pt-year] (group A 33.6 {25.3-41.8}, group B 24.1 {18.9-29.23}). Group A had higher number of hospitalization days (P = 0.012) for surgery or trauma and higher rate (P = 0.045) and days (P = 0.041) of hospitalization for miscellaneous causes, primarily pulmonary disease, or malignancy. Among diabetic patients, group A had only a greater number of hospital days for cardiac disease (P = 0.050). Among patients without diabetes, group A had a higher number for hospital days for surgery or trauma (P = 0.027). All other univariate comparisons were not significant. Multiple linear regression identified comorbidity, quantified by the Charlson index, Caucasian race and poor compliance with the HD schedule as predictors of admission rate and days per year for vascular access issues and comorbidity, poor compliance, and advanced age at onset of HD as predictors of admission for causes other than vascular access related.

CONCLUSION

Hospitalizations, which affect quality of life, differ little between elderly and younger patients on HD. Therefore, hospitalizations do not constitute an argument for restricting access to HD to elderly patients.

摘要

背景

本研究旨在确定慢性血液透析(HD)患者中,每年每位患者的住院次数(n/[pt-yr])和每年每位患者的住院天数(d/[pt-yr])是否因年龄而异。

方法

在一个透析单位的回顾性队列分析中,我们比较了 166 名年龄超过 70 岁(77.1±4.7 岁)的 HD 起始时的老年患者(A 组)和 216 名年龄小于 70 岁的患者(57.1±7.6 岁),比较了他们在 HD 起始时和结束时的情况。A 组中 80 例(48.2%)和 B 组中 141 例(65.3%)患有糖尿病。

结果

总体住院率(以平均值表示,95%置信区间)在两组间无差异,A 组为 2.40(2.04-2.75),B 组为 2.03(1.89-2.16)n/[pt-yr])和每天/[pt-yr](A 组 33.6(25.3-41.8),B 组 24.1(18.9-29.23))。A 组的手术或创伤住院天数(P=0.012)和非手术相关原因的住院率(P=0.045)和住院天数(P=0.041)较高,主要是肺部疾病或恶性肿瘤。在糖尿病患者中,A 组仅因心脏病住院天数较多(P=0.050)。在非糖尿病患者中,A 组因手术或创伤而住院的天数较多(P=0.027)。所有其他单变量比较均无统计学意义。多元线性回归确定了合并症,由 Charlson 指数量化,白种人种族和不遵守 HD 时间表是血管通路问题和合并症入院率和每年天数的预测因素,不遵守 HD 时间表和高龄是血管通路以外原因入院的预测因素。

结论

HD 患者的住院治疗,影响生活质量,在老年和年轻患者之间差异不大。因此,住院治疗并不是限制老年患者接受 HD 的理由。

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