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美国透析患者的住院情况:血液透析与腹膜透析对比

Hospitalization among United States dialysis patients: hemodialysis versus peritoneal dialysis.

作者信息

Habach G, Bloembergen W E, Mauger E A, Wolfe R A, Port F K

机构信息

Department of Internal Medicine, School of Medicine, University of Michigan, Ann Arbor, USA.

出版信息

J Am Soc Nephrol. 1995 May;5(11):1940-8. doi: 10.1681/ASN.V5111940.

Abstract

Measurements of hospitalization in the dialysis population are important because they provide insight into the morbidity and the cost of treatment among dialysis patients. Prior comparisons of hospitalization for different dialysis modalities have had conflicting results. This study was designed to compare hospitalization for patients treated with peritoneal dialysis (PD) versus hemodialysis (HD) using the data from the U.S. Renal Data System 1993 Annual Data Report. The study population included all Medicare dialysis patients prevalent on January 1, 1988 through 1990. Patients were monitored to transplantation, death, or end of the calendar year for a total of 189,654 patient years. Hospital admission rates were computed from the total number of hospital admissions during the year divided by the total number of patient years at risk. Patients were classified by treatment modality (PD, HD), cause of ESRD (diabetes as a cause of ESRD versus all other causes), age (0 to 19, 20 to 44, 45 to 65, +65), and race (black, white). Rate ratios (RR:PD/HD) for hospital admissions per year at risk were estimated, while adjusting for the other factors with Poison regression. On average, hospital admission rates per patient year at risk for dialysis patients treated with PD were 14% higher than for those treated with HD (RR = 1.14; 95% confidence interval (Cl), 1.13 to 1.15) when adjusting for race, age, gender, and cause of ESRD. The excess in the overall adjusted admission rates in PD patients compared with HD patients was higher for black than for white patients (RR:PD/HD = 1.22 versus RR = 1.11; 95% Cl, 1.10 to 1.13).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

对透析人群的住院情况进行测量很重要,因为这能让我们深入了解透析患者的发病率和治疗成本。此前针对不同透析方式的住院情况比较结果相互矛盾。本研究旨在利用美国肾脏数据系统1993年年报中的数据,比较接受腹膜透析(PD)和血液透析(HD)治疗的患者的住院情况。研究人群包括1988年1月1日至1990年期间所有的医疗保险透析患者。对患者进行监测,直至其移植、死亡或到历年结束,总计189,654患者年。住院率通过当年住院总数除以处于风险中的患者年总数来计算。患者按治疗方式(PD、HD)、终末期肾病病因(糖尿病作为终末期肾病病因与所有其他病因)、年龄(0至19岁、20至44岁、45至65岁、65岁以上)和种族(黑人、白人)进行分类。在通过泊松回归对其他因素进行校正的同时,估算每年处于风险中的患者的住院率比(RR:PD/HD)。校正种族、年龄、性别和终末期肾病病因后发现,接受PD治疗的透析患者每患者年的平均住院率比接受HD治疗的患者高14%(RR = 1.14;95%置信区间(Cl),1.13至1.15)。与HD患者相比,PD患者总体校正后住院率的超额部分在黑人患者中高于白人患者(RR:PD/HD = 1.22,而RR = 1.11;95% Cl,1.10至1.13)。(摘要截断于250字)

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