Aggarwal A, Kumhar G Das, Harit D, Faridi M M A
Department of Pediatrics, University College of Medical Sciences, Guru Tegh Bahadur Hospital, Delhi, India.
J Prev Med Hyg. 2010 Sep;51(3):131-2.
Folic acid supplementation is important in the prevention of Neural Tube Defects (NTD). The study was conducted to assess the awareness amongst physicians regarding the role of Folic Acid (FA) in the prevention of NTD. Physicians were interviewed regarding the awareness of FA dose, timing of supplementation and knowledge about its role in prevention of neural tube defects using a semistructured questionnaire. Among 202 physicians interviewed (48 pediatricians, 54 obstetricians, 100 recently qualified medical graduates) overall awareness about FA was present in 92.07%, similar in three groups (P > 0.05). Only 47.52% were aware of preconception administration, 61.38% about dose of supplementation and 11.88% about recurrence rate of NTD. Only 15 (7.4%) knew all these. Regarding the etiology of NTDs only 26.7% said both FA and genetic factors are involved. Though majority were aware that folic acid has a role in prevention of NTDs, their knowledge about timing and dose of supplementation was lacking. Hence attempts should be made to increase the awareness regarding prevention of NTD's by FA supplementation at a proper time.
补充叶酸对预防神经管缺陷（NTD）很重要。本研究旨在评估医生对叶酸（FA）在预防NTD中作用的认知情况。使用半结构化问卷就FA剂量、补充时间以及其在预防神经管缺陷中作用的相关知识对医生进行访谈。在接受访谈的202名医生中（48名儿科医生、54名产科医生、100名近期合格的医学毕业生），对FA的总体认知率为92.07%，三组情况相似（P>0.05）。只有47.52%的人知晓孕前给药，61.38%的人了解补充剂量，11.88%的人知道NTD的复发率。只有15人（7.4%）了解所有这些。关于NTD的病因，只有26.7%的人表示FA和遗传因素都有关。尽管大多数人知道叶酸在预防NTD中起作用，但他们缺乏关于补充时间和剂量的知识。因此，应努力提高人们对在适当时间通过补充FA预防NTD的认识。
