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非调强放射治疗临床放射治疗中监测器单位计算的验证:AAPM 工作组 114 报告。

Verification of monitor unit calculations for non-IMRT clinical radiotherapy: report of AAPM Task Group 114.

机构信息

Department of Radiation Oncology, University of California, Davis, Sacramento, California 95817, USA.

出版信息

Med Phys. 2011 Jan;38(1):504-30. doi: 10.1118/1.3521473.

Abstract

The requirement of an independent verification of the monitor units (MU) or time calculated to deliver the prescribed dose to a patient has been a mainstay of radiation oncology quality assurance. The need for and value of such a verification was obvious when calculations were performed by hand using look-up tables, and the verification was achieved by a second person independently repeating the calculation. However, in a modern clinic using CT/MR/PET simulation, computerized 3D treatment planning, heterogeneity corrections, and complex calculation algorithms such as convolution/superposition and Monte Carlo, the purpose of and methodology for the MU verification have come into question. In addition, since the verification is often performed using a simpler geometrical model and calculation algorithm than the primary calculation, exact or almost exact agreement between the two can no longer be expected. Guidelines are needed to help the physicist set clinically reasonable action levels for agreement. This report addresses the following charges of the task group: (1) To re-evaluate the purpose and methods of the "independent second check" for monitor unit calculations for non-IMRT radiation treatment in light of the complexities of modern-day treatment planning. (2) To present recommendations on how to perform verification of monitor unit calculations in a modern clinic. (3) To provide recommendations on establishing action levels for agreement between primary calculations and verification, and to provide guidance in addressing discrepancies outside the action levels. These recommendations are to be used as guidelines only and shall not be interpreted as requirements.

摘要

对监视器单位 (MU) 或计算得出的时间进行独立验证以将规定剂量输送给患者的要求一直是放射肿瘤学质量保证的基础。当使用查找表手动进行计算并且通过第二个人独立重复计算来实现验证时,对这种验证的需求和价值是显而易见的。然而,在现代临床实践中,使用 CT/MR/PET 模拟、计算机化 3D 治疗计划、不均匀性校正以及卷积/叠加和蒙特卡罗等复杂计算算法,MU 验证的目的和方法受到了质疑。此外,由于验证通常使用比主要计算更简单的几何模型和计算算法,因此不能再期望两者之间完全一致或几乎完全一致。需要指南来帮助物理学家为协议设置临床合理的行动水平。本报告针对任务组的以下指控:(1) 根据现代治疗计划的复杂性,重新评估非调强放疗的监视器单位计算的“独立二次检查”的目的和方法。(2) 介绍如何在现代临床实践中进行监视器单位计算验证的建议。(3) 提供用于确定主要计算和验证之间一致性的行动水平的建议,并提供解决超出行动水平的差异的指导。这些建议仅用作指南,不应被解释为要求。

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