Department of Cardiology, Affiliated Hospital of Nanjing Medical University in Wuxi and Wuxi People's Hospital, Wuxi, Jiangsu 214023, China.
Chin Med J (Engl). 2011 Feb;124(3):436-9.
Cardiac resynchronization therapy (CRT) is a major breakthrough in therapy for patients with advanced congestive heart failure, however, a number of key clinical research questions remain, perhaps most importantly the issue of why apparently suitable patients do not respond to CRT. These issues are also relevant to patients who do respond to CRT as potentially their response might be further increased. Though patients do not respond to CRT because of many known postulated reasons, we review the importance of maintaining atrioventricular intrinsic conduction during CRT in this paper, which maybe is one of methods to reduce the rates of non-response to CRT.
心脏再同步治疗（CRT）是治疗晚期充血性心力衰竭患者的重大突破，然而，仍有许多关键的临床研究问题悬而未决，也许最重要的问题是为什么显然适合的患者对 CRT 没有反应。这些问题也与对 CRT 有反应的患者有关，因为他们的反应可能进一步增加。虽然由于许多已知的推测原因，患者对 CRT 没有反应，但我们在本文中回顾了在 CRT 期间保持房室内在传导的重要性，这可能是降低 CRT 无反应率的方法之一。
