经杀虫剂处理的蚊帐（ITMNs）对猪和人类日本脑炎病毒血清转化的影响。
The effect of insecticide-treated mosquito nets (ITMNs) on Japanese encephalitis virus seroconversion in pigs and humans.
作者信息
Dutta Prafulla, Khan Siraj A, Khan Abdul M, Borah Jani, Sarmah Chandra K, Mahanta Jagadish
机构信息
Regional Medical Research Centre, Indian Council of Medical Research, Division of Entomology and Filariasis, North East Region, Dibrugarh, Assam, India.
出版信息
Am J Trop Med Hyg. 2011 Mar;84(3):466-72. doi: 10.4269/ajtmh.2011.10-0270.
The effect of insecticide-treated mosquito nets (ITMNs) on Japanese Encephalitis (JE) virus seroconversion in pigs and humans was studied in Assam, Northeast India. A sharp reduction of seroconversion rate in human and pig was found in treated localities after intervention. A marked reduction was achieved in humans (risk ratio [RR] = 0.28, 95% confidence interval [CI] = 0.16-0.49) and pigs (RR = 0.21, CI = 0.11-0.40) in the Kollolua locality where ITMNs were used on both humans and pigs compared with the other two area, Athabari and Rajmai, where ITMNs were covering only either humans or pigs. Monitoring of the mosquito population in and around cattle sheds during dusk revealed no significant decline (P > 0.05) of vector density during the post-intervention period in study localities. In spite of the high preponderance of potential JE vector outdoors during the post-intervention period, an encouraging line of defense against circulation of JE virus through the use of ITMNs can be achieved in endemic areas.
在印度东北部的阿萨姆邦，研究了经杀虫剂处理的蚊帐（ITMNs）对猪和人类日本脑炎（JE）病毒血清转化的影响。干预后，在使用ITMNs的地区，人类和猪的血清转化率急剧下降。在Kollolua地区，人与猪均使用了ITMNs，与仅对人类或猪使用ITMNs的另外两个地区Athabari和Rajmai相比，人类（风险比[RR]=0.28，95%置信区间[CI]=0.16 - 0.49）和猪（RR = 0.21，CI = 0.11 - 0.40）的血清转化率显著降低。黄昏时分对牛棚内外蚊虫种群的监测显示，研究地区干预后病媒密度没有显著下降（P>0.05）。尽管干预后潜在的日本脑炎病媒在户外占比很高，但在流行地区通过使用ITMNs可以实现一条令人鼓舞的针对日本脑炎病毒传播的防线。
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