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[静息状态下的大脑功能活动:连接网络]

[Functional cerebral activity in a state of rest: connectivity networks].

作者信息

Proal Erika, Alvarez-Segura Mar, de la Iglesia-Vayá María, Martí-Bonmatí Luis, Castellanos F Xavier

机构信息

Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center, NYU School of Medicine, 215 Lexington Ave., New York, NY 10016, USA.

出版信息

Rev Neurol. 2011 Mar 1;52 Suppl 1(0 1):S3-10.

Abstract

Functional connectivity can be measured during task-based functional magnetic resonance imaging (fMRI), or in the absence of specific stimuli or tasks. In either case, the study of low frequency fluctuations in the BOLD signal reveals patterns of synchronization which delineate the intrinsic functional architecture of the brain. The scientific community now has available shared resources to accelerate the exploitation of resting state fMRI with the objectives of improving diagnostic methods and leading to better treatments grounded in neuroscience. Fomenting a collaborative scientific culture will accelerate our understanding of the underlying phenonmemna. Recently, the Spanish Resting State Network (SRSN) has joined this collaborative effort by creating a setting to facilitate collaboration among the various neuroscience research groups working in Spanish (http://www.nitrc.org/projects/srsn).

摘要

功能连接性可以在基于任务的功能磁共振成像(fMRI)期间进行测量,也可以在没有特定刺激或任务的情况下进行测量。在任何一种情况下,对血氧水平依赖(BOLD)信号中的低频波动进行研究,都能揭示出同步模式,这些模式描绘了大脑的内在功能结构。科学界现在有了共享资源,以加速对静息态fMRI的利用,目标是改进诊断方法,并基于神经科学实现更好的治疗。培育合作性的科学文化将加速我们对潜在现象的理解。最近,西班牙静息态网络(SRSN)通过创建一个促进西班牙各神经科学研究小组之间合作的平台,加入了这一合作努力(http://www.nitrc.org/projects/srsn)。

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