• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

5-甲氧基马兜铃内酰胺I,首个从宜昌细辛中分离得到的天然5-取代马兜铃内酰胺。

5-methoxyaristololactam I, the first natural 5-substituted aristololactam from Asarum ichangense.

作者信息

Xie Bai-Bo, Shang Ming-Ying, Lee Kuo-Hsiung, Wang Xuan, Komatsu Katsuko, Cai Shao-Qing

机构信息

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, PR China.

出版信息

Nat Prod Commun. 2011 Jan;6(1):11-4.

PMID:21366036
Abstract

A new aristololactam, 5-methoxyaristololactam I (1), was isolated from an ethanol extract of the whole plant of Asarum ichangense C. Y. Cheng et C. S. Yang, together with twenty known compounds (2-21). The structure of 1 was elucidated by spectroscopic methods. Compounds 11, 13, 17, and 19 were isolated from Aristolochiaceae for the first time. Compounds 2, 14, and 15 are considered as common constituents of the genus Asarum.

摘要

从宜昌细辛(Asarum ichangense C. Y. Cheng et C. S. Yang)全草的乙醇提取物中分离得到一种新的马兜铃内酰胺,5-甲氧基马兜铃内酰胺I(1),以及二十种已知化合物(2 - 21)。通过光谱方法阐明了1的结构。化合物11、13、17和19首次从马兜铃科植物中分离得到。化合物2、14和15被认为是细辛属的常见成分。

相似文献

1
5-methoxyaristololactam I, the first natural 5-substituted aristololactam from Asarum ichangense.5-甲氧基马兜铃内酰胺I,首个从宜昌细辛中分离得到的天然5-取代马兜铃内酰胺。
Nat Prod Commun. 2011 Jan;6(1):11-4.
2
[Studies on the chemical constituents from Asarum Chinese Franch. f. fargesii (Franch.) C. Y. Cheng (II)].
Zhong Yao Cai. 2006 Feb;29(2):130-2.
3
A new amide from Asarum forbesii Maxim.
J Asian Nat Prod Res. 2005 Feb;7(1):1-5. doi: 10.1080/10286020310001596015.
4
[A new aristolochic acid derivative from Asarum himalaicum].
Yao Xue Xue Bao. 2011 Feb;46(2):188-92.
5
Phenanthrene derivatives from roots and rhizomes of Asarum heterotropoides var. mandshuricum.北细辛根及根茎中的菲衍生物。
Fitoterapia. 2017 Mar;117:101-108. doi: 10.1016/j.fitote.2017.01.008. Epub 2017 Jan 24.
6
Chemical Constituents from the Roots and Rhizomes of Asarum heterotropoides var. mandshuricum and the In Vitro Anti-Inflammatory Activity.辽细辛根及根茎的化学成分与体外抗炎活性
Molecules. 2017 Jan 13;22(1):125. doi: 10.3390/molecules22010125.
7
Chemistry and biology of non-tetramic gamma-hydroxy-gamma-lactams and gamma-alkylidene-gamma-lactams from natural sources.天然来源的非四元γ-羟基-γ-内酰胺和γ-亚烷基-γ-内酰胺的化学与生物学特性
Nat Prod Rep. 2009 Aug;26(8):1044-62. doi: 10.1039/b903905h. Epub 2009 Jun 11.
8
Four new compounds from the roots of Uvaria macrophylla.来自大花紫玉盘根中的四种新化合物。
J Asian Nat Prod Res. 2005 Oct;7(5):687-94. doi: 10.1080/10286020412331286524.
9
Asaroidoxazines from the Roots of Induce Apoptosis in Human Neuroblastoma Cells.从苦豆根中分离得到的槐定碱诱导人神经母细胞瘤细胞凋亡。
J Nat Prod. 2020 Oct 23;83(10):3050-3057. doi: 10.1021/acs.jnatprod.0c00574. Epub 2020 Sep 21.
10
Antiprotealide is a natural product.抗蛋白酶肽是一种天然产物。
J Nat Prod. 2009 Feb 27;72(2):295-7. doi: 10.1021/np800578e.

引用本文的文献

1
Comparative Biochemical and Pharmacodynamic Analyses of Fr. Schmidt var. Mandshuricum (Maxim) Kitag and Miq var. Seoulense Nakai Roots.刺人参变种(Maxim)Kitag和汉城细辛变种(Miq var. Seoulense Nakai)根的比较生化与药效学分析
Pharmaceuticals (Basel). 2024 Sep 30;17(10):1301. doi: 10.3390/ph17101301.
2
Asatone and Isoasatone A Against Fab. by Acting on Cytochrome P450 Monoxygenases and Glutathione Transferases.Asatone 和 Isoasatone A 通过作用于细胞色素 P450 单加氧酶和谷胱甘肽转移酶来抑制 Fab。
Molecules. 2019 Oct 31;24(21):3940. doi: 10.3390/molecules24213940.
3
Chemical Constituents from the Roots and Rhizomes of Asarum heterotropoides var. mandshuricum and the In Vitro Anti-Inflammatory Activity.
辽细辛根及根茎的化学成分与体外抗炎活性
Molecules. 2017 Jan 13;22(1):125. doi: 10.3390/molecules22010125.