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5-甲氧基马兜铃内酰胺I,首个从宜昌细辛中分离得到的天然5-取代马兜铃内酰胺。

5-methoxyaristololactam I, the first natural 5-substituted aristololactam from Asarum ichangense.

作者信息

Xie Bai-Bo, Shang Ming-Ying, Lee Kuo-Hsiung, Wang Xuan, Komatsu Katsuko, Cai Shao-Qing

机构信息

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, PR China.

出版信息

Nat Prod Commun. 2011 Jan;6(1):11-4.

Abstract

A new aristololactam, 5-methoxyaristololactam I (1), was isolated from an ethanol extract of the whole plant of Asarum ichangense C. Y. Cheng et C. S. Yang, together with twenty known compounds (2-21). The structure of 1 was elucidated by spectroscopic methods. Compounds 11, 13, 17, and 19 were isolated from Aristolochiaceae for the first time. Compounds 2, 14, and 15 are considered as common constituents of the genus Asarum.

摘要

从宜昌细辛(Asarum ichangense C. Y. Cheng et C. S. Yang)全草的乙醇提取物中分离得到一种新的马兜铃内酰胺,5-甲氧基马兜铃内酰胺I(1),以及二十种已知化合物(2 - 21)。通过光谱方法阐明了1的结构。化合物11、13、17和19首次从马兜铃科植物中分离得到。化合物2、14和15被认为是细辛属的常见成分。

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