Grigolon Ausilia, Consonni Dario, Bravi Ivana, Tenca Andrea, Penagini Roberto
Cattedra di Gastroenterologia, Università degli Studi and Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Scand J Gastroenterol. 2011 May;46(5):522-30. doi: 10.3109/00365521.2010.545834. Epub 2011 Mar 3.
To get insight into usefulness of 96-h wireless monitoring in diagnosis of gastro-esophageal reflux disease (GERD) and in patients' management.
51 patients who underwent 96-h wireless and 51 matched patients who underwent 24-h traditional pH monitoring were enrolled and retrospectively contacted with a structured telephone interview.
In the wireless group, the 96-h recording improved (p < 0.05) the diagnostic yield compared with the first 48-h recording by allowing Symptom Association Probability to be measured in eight more patients and by decreasing indeterminate tests from 11 to 5. After pH monitoring, concordance between results of the test and treatment for GERD was higher in the wireless compared with the traditional group, 78% versus 58% of the patients (p < 0.05). Both improvement/disappearance of the clinically relevant symptom and satisfaction (score of 1-10) at time of the telephone interview were however similar in the two groups, 73% versus 65% and 7.0 versus 6.5.
Wireless pH monitoring prolonged to 96 h increased the likelihood to exclude/confirm GERD as the cause of the clinically relevant symptoms in those patients with an indeterminate result for GERD after the first 48 h. Outcome was however similar to the one of traditional pH monitoring.
深入了解96小时无线监测在胃食管反流病（GERD）诊断及患者管理中的作用。
纳入51例接受96小时无线监测的患者以及51例匹配的接受24小时传统pH监测的患者，并通过结构化电话访谈进行回顾性联系。
在无线监测组中，与最初48小时记录相比，96小时记录提高了（p < 0.05）诊断率，使得另外8例患者能够进行症状关联概率测量，并将不确定测试从11例减少至5例。pH监测后，无线监测组中GERD测试结果与治疗的一致性高于传统监测组，患者分别为78%和58%（p < 0.05）。然而，两组在电话访谈时临床相关症状的改善/消失情况以及满意度（1 - 10分）相似，分别为73%对65%以及7.0对6.5。
将无线pH监测延长至96小时增加了在最初48小时GERD结果不确定的患者中排除/确认GERD为临床相关症状病因的可能性。然而，结果与传统pH监测相似。
