Fundamental Science Directorate, Pacific Northwest National Laboratory, Richland, Washington 99352, USA.
Annu Rev Anal Chem (Palo Alto Calif). 2011;4:83-104. doi: 10.1146/annurev-anchem-061010-114028.
Soft and reactive landing of mass-selected ions onto surfaces has become a topic of substantial interest due to its promising potential for the highly controlled preparation of materials. For example, there are possible applications in the production of peptide and protein microarrays for use in high-throughput screening, protein separation and conformational enrichment of peptides, redox protein characterization, thin-film production, and the preparation of catalysts through deposition of clusters and organometallic complexes. Soft landing overcomes many of the limitations associated with conventional thin-film production techniques and offers unprecedented selectivity and specificity of preparation of deposited species. This review discusses the fundamental aspects of soft and reactive landing of mass-selected ions on surfaces that pertain to applications of these techniques in biomaterials, molecular electronics, catalysis, and interfacial chemistry.
由于其在高度可控的材料制备方面具有广阔的应用前景，因此对质量选择的离子在表面上的软着陆和反应性研究已成为一个热门话题。例如，它在用于高通量筛选的肽和蛋白质微阵列的生产、肽的高选择性分离和构象富集、氧化还原蛋白质特性分析、薄膜生产以及通过团簇和有机金属配合物的沉积制备催化剂等方面都有潜在的应用。软着陆克服了传统薄膜生产技术的许多局限性，并为沉积物种的制备提供了前所未有的选择性和特异性。本综述讨论了质量选择的离子在表面上软着陆和反应性的基本方面，这些方面与这些技术在生物材料、分子电子学、催化和界面化学中的应用有关。
