Division of Neurology, Cleveland Clinic, Cleveland, OH 44016, USA.
Int J Stroke. 2011 Apr;6(2):136-43. doi: 10.1111/j.1747-4949.2010.00568.x. Epub 2011 Jan 10.
The incidence of syphilis has increased over the past decade, particularly among HIV-positive patients, and the presenting clinical features have changed since the beginning of the HIV epidemic. The clinical manifestations of neurosyphilis are protean, and include acute stroke. In patients with HIV, the diagnosis and treatment of neurosyphilis is challenging. We review the clinical presentation, pathophysiology, and treatment of neurosyphilis, with emphasis on neurosyphilis in the HIV population, and neurosyphilis as a cause of acute stroke.
过去十年间，梅毒的发病率有所上升，尤其是在 HIV 阳性患者中，且自艾滋病流行开始以来，其临床表现也发生了变化。神经梅毒的临床表现多种多样，包括急性脑卒中。在 HIV 感染者中，神经梅毒的诊断和治疗颇具挑战性。我们回顾了神经梅毒的临床表现、病理生理学和治疗方法，重点介绍了 HIV 人群中的神经梅毒和神经梅毒导致急性脑卒中的情况。
