对一种菲律宾本土植物的化学研究：菲律宾五桠果中的硫酸化葡萄糖苷和裂环A环三萜类化合物。
Chemical studies on an endemic Philippine plant: sulfated glucoside and seco-A-ring triterpenoids from Dillenia philippinensis.
作者信息
Macahig Rene Angelo Sarmiento, Matsunami Katsuyoshi, Otsuka Hideaki
机构信息
Department of Pharmacognosy, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
出版信息
Chem Pharm Bull (Tokyo). 2011;59(3):397-401. doi: 10.1248/cpb.59.397.
The leaves of the endemic Philippine plant, Dillenia philippinensis yielded 11 compounds including one new sulfated glucoside and a new seco-A-ring oleanane-type triterpenoid. The molecular structures of these compounds were elucidated by means of NMR, MS and other spectroscopic techniques, as well as by comparison with literature data. Anti-Leishmania activity and cytotoxic activity against A549 human lung adenocarcinoma cells were also examined.
菲律宾本土植物菲律宾五桠果的叶子产生了11种化合物，包括一种新的硫酸化葡糖苷和一种新的裂环A环齐墩果烷型三萜类化合物。通过核磁共振（NMR）、质谱（MS）和其他光谱技术，以及与文献数据比较，阐明了这些化合物的分子结构。还检测了其抗利什曼原虫活性和对A549人肺腺癌细胞的细胞毒性活性。
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