Pangaea Global AIDS Foundation, Oakland, CA, USA.
J Acquir Immune Defic Syndr. 2011 Jul 1;57(3):e33-9. doi: 10.1097/QAI.0b013e3182167e90.
Human resource shortages are viewed as one of the primary obstacles to provide effective services to growing patient populations receiving antiretroviral therapy (ART) and to expand ART access further. We examined the relationship of patient volume, human resource levels, and patient characteristics with attrition from HIV treatment programs in central Mozambique.
We conducted a retrospective cohort study of adult, ART-naive, nonpregnant patients who initiated ART between January 2006 and June 2008 in the national HIV care program. Cox proportional hazards models were used to assess the association of patient volume, clinical staff burden, and pharmacy staff burden with attrition, adjusting for patient characteristics.
A total of 11,793 patients from 18 clinics were studied. After adjusting for patient characteristics, patients attending clinics with medium pharmacy staff burden [hazard ratio (HR) = 1.39 (95% CI: 1.07 to 1.80)] and high pharmacy staff burden [HR = 2.09 (95% CI: 1.50 to 2.91)] tended to have a higher risk of attrition (P value for trend: <0.001). Patients attending clinics with higher clinical staff burden did not have a statistically higher risk of attrition. Patients attending clinics with medium patient volume levels [HR = 1.45 (95% CI: 1.04 to 2.04)] and high patient volume levels [HR = 1.41 (95% CI: 1.04 to 1.92)] had a higher risk of attrition, but the trend test was not significant (P = 0.198).
Patients attending clinics with higher pharmacy staff burden had a higher risk of attrition. These results highlight a potential area within the health system where interventions could be applied to improve the retention of these patient populations.
人力资源短缺被视为为接受抗逆转录病毒疗法 (ART) 的不断增长的患者群体提供有效服务并进一步扩大 ART 获得途径的主要障碍之一。我们研究了莫桑比克中部地区患者数量、人力资源水平和患者特征与艾滋病毒治疗项目流失之间的关系。
我们对 2006 年 1 月至 2008 年 6 月期间在国家艾滋病毒护理计划中首次接受抗逆转录病毒治疗的成年、抗逆转录病毒治疗初治、非妊娠患者进行了回顾性队列研究。使用 Cox 比例风险模型评估了患者数量、临床工作人员负担和药剂师工作人员负担与流失之间的关联,同时调整了患者特征。
共研究了来自 18 个诊所的 11793 名患者。在调整了患者特征后,到中等药剂师人员负担 [风险比 (HR) = 1.39 (95%置信区间:1.07 至 1.80)] 和高药剂师人员负担 [HR = 2.09 (95%置信区间:1.50 至 2.91)] 的诊所就诊的患者更有可能流失(趋势检验 P 值:<0.001)。到具有较高临床工作人员负担的诊所就诊的患者并没有更高的流失风险。到中等患者量水平 [HR = 1.45 (95%置信区间:1.04 至 2.04)] 和高患者量水平 [HR = 1.41 (95%置信区间:1.04 至 1.92)] 的诊所就诊的患者更有可能流失,但趋势检验不显著(P = 0.198)。
到药剂师人员负担较高的诊所就诊的患者更有可能流失。这些结果突出了卫生系统中一个潜在的领域,在这个领域可以实施干预措施,以提高这些患者群体的保留率。