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布基纳法索农村地区新生儿死亡及其预测因素的前瞻性研究:2015 年能实现千年发展目标 4 吗?

A prospective study on neonatal mortality and its predictors in a rural area in Burkina Faso: can MDG-4 be met by 2015?

机构信息

Centre MURAZ Research Institute, Ministry of Health/Burkina Faso, Bobo-Dioulasso, Burkina Faso.

出版信息

J Perinatol. 2011 Oct;31(10):656-63. doi: 10.1038/jp.2011.6. Epub 2011 Mar 3.

Abstract

OBJECTIVE

To measure the neonatal mortality rate (NMR) and investigate its predictors in a rural area of Burkina Faso.

STUDY DESIGN

A cohort of infants born in 24 villages in Banfora region was followed until the children were 6 months old. We estimated the risk of neonatal death and used logistic regression to identify its predictors.

RESULT

Among 864 live births followed to day 28, there were 40 neonatal deaths, a NMR of 46.3 per 1000 live births (95% confidence intervals (CI): 22 to 70). Multivariable regression identified twin birth (OR=11.5, 95% CI: 4.5 to 29.8), having a nulliparous mother (odds ratio (OR)=4.3, 95% CI: 1.5 to 12.1), and birth into a polygynous household (OR=2.1, 95% CI: 1.0 to 4.7) as main predictors of neonatal death.

CONCLUSION

The burden of neonatal mortality in rural Burkina Faso is very high and the observed NMRs in a predominantly rural country suggest that it is unlikely Burkina will meet fourth Millennium Development Goal (MDG-4) by 2015.

摘要

目的

在布基纳法索的一个农村地区测量新生儿死亡率(NMR)并调查其预测因素。

研究设计

对班福拉地区 24 个村庄出生的婴儿队列进行了随访,直到孩子 6 个月大。我们估计了新生儿死亡的风险,并使用逻辑回归来确定其预测因素。

结果

在随访至 28 天的 864 例活产儿中,有 40 例新生儿死亡,新生儿死亡率为每 1000 例活产儿 46.3 例(95%置信区间(CI):22 至 70)。多变量回归确定了双胞胎分娩(OR=11.5,95%CI:4.5 至 29.8)、初产妇(比值比(OR)=4.3,95%CI:1.5 至 12.1)和多配偶家庭出生(OR=2.1,95%CI:1.0 至 4.7)是新生儿死亡的主要预测因素。

结论

布基纳法索农村地区新生儿死亡率的负担非常高,观察到的主要农村国家的 NMR 表明,布基纳法索不太可能在 2015 年实现第四个千年发展目标(MDG-4)。

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