Garman Katherine S, Shaheen Nicholas J
Division of Gastroenterology, Institute for Genome Science and Policy, Duke University, Box 3913 DUMC, Durham, NC 27710, USA.
Curr Gastroenterol Rep. 2011 Jun;13(3):226-39. doi: 10.1007/s11894-011-0182-z.
Barrett's esophagus has gained increased clinical attention because of its association with esophageal adenocarcinoma, a cancer with increasing incidence and poor survival rates. The goals of ablating Barrett's esophagus are to decrease esophageal cancer rates and to improve overall survival and quality of life. Different techniques have been developed and tested for their effectiveness eradicating Barrett's epithelium. This review assesses the literature associated with different ablative techniques. The safety and efficacy of different techniques are discussed. This review concludes with recommendations for the clinician, including specific strategies for patient care decisions for patients with Barrett's esophagus with varying degrees of dysplasia.
巴雷特食管因其与食管腺癌相关而受到越来越多的临床关注，食管腺癌的发病率不断上升且生存率较低。消融巴雷特食管的目的是降低食管癌发病率，提高总体生存率和生活质量。已经开发并测试了不同技术以评估其根除巴雷特上皮的有效性。本综述评估了与不同消融技术相关的文献。讨论了不同技术的安全性和有效性。本综述最后为临床医生提供了建议，包括针对不同程度发育异常的巴雷特食管患者的具体患者护理决策策略。
