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[幕上脑肿瘤患者手术期间及术后脑室系统脑脊液压力测量]

[Cerebrospinal fluid pressure measurements in the ventricular system during and after surgery in patients with supratentorial brain tumors].

作者信息

Koźniewska H, Moszyński K, Lewelt W, Darwaj B

出版信息

Neurol Neurochir Pol. 1978 Jul-Aug;12(4):463-70.

PMID:213739
Abstract

In the light of CSFP measurements by Lundberg's method in 46 patients the authors showed the role of hyperventilation in lowering of intracranial pressure. A considerable efficacy of dexamethasone was demonstrated as well, the use of this drug permitted to achieve stabilization of CSFP during and after the operation. The investigations showed a considerable effectiveness of such drugs as mannitol and furosemide in lowering of CSFP. Pancuronium was found to be superior to suxamethonium for administration during induction of anaesthesia because the former caused no CSFP rise. In polygraphic investigations of nocturnal sleep with parallel recording of CSFP a rise of CSFP was demonstrated during REM phase of sleep.

摘要

根据伦德伯格方法对46例患者进行的脑脊液压力(CSFP)测量,作者揭示了过度换气在降低颅内压中的作用。同时还证明了地塞米松具有显著疗效,使用该药物可使手术期间及术后的脑脊液压力稳定。研究表明,甘露醇和呋塞米等药物在降低脑脊液压力方面具有显著效果。发现泮库溴铵在麻醉诱导期间给药优于琥珀胆碱,因为前者不会引起脑脊液压力升高。在对夜间睡眠进行多导记录并同步记录脑脊液压力的研究中,发现在快速眼动睡眠期脑脊液压力会升高。

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