Hui Guohua, Zhao Zikai
College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310035, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2010 Dec;27(6):1406-9.
As a novel BioChip technique, LiquiChip technique uses fluorescent polystyrene beads as the carrriers of various probes, thus the related reactions of bio-molecules are in liquid system. LiquiChip technique is of use in the methods to detect bio-macromolecules, e. g. DNA detection, immunoassay, cytokine assay, hormone assay, environmental survey and analysis. In comparison to conventional biochip, LiquiChip presents the advantages of high-throughput, high sensitivity, high accuracy, fine repeatability, wide linear range, etc. Now LiquiChip technique is widely used in biomedical engineering field.
作为一种新型生物芯片技术,液相芯片技术使用荧光聚苯乙烯微球作为各种探针的载体,因此生物分子的相关反应在液体体系中进行。液相芯片技术可用于检测生物大分子的方法,如DNA检测、免疫测定、细胞因子测定、激素测定、环境检测与分析等。与传统生物芯片相比,液相芯片具有高通量、高灵敏度、高精度、重复性好、线性范围宽等优点。目前,液相芯片技术在生物医学工程领域得到了广泛应用。