Unité 872, Institut National de la Santé et de la Recherche Médicale Paris, F-75006, France.
Autoimmun Rev. 2011 Oct;10(12):809-10. doi: 10.1016/j.autrev.2011.02.007. Epub 2011 Mar 2.
Variations in intravenous immunoglobulin (IVIg) products are a common feature. In this report, we compared the effect of different IVIg products on IL-17 production by human Th17 cells. We found that irrespective of products, IgGs of all IVIg preparations were equally effective in inhibiting the production of IL-17A from Th17 cells.
静脉注射免疫球蛋白 (IVIg) 产品存在差异是常见现象。在本报告中,我们比较了不同 IVIg 产品对人 Th17 细胞产生白介素-17 (IL-17) 的影响。结果发现,无论产品如何,所有 IVIg 制剂的 IgG 均能有效抑制 Th17 细胞产生 IL-17A。