分离一种新型伴放线放线杆菌 b 型噬菌体能在生物膜内裂解细菌。
Isolation of a novel Aggregatibacter actinomycetemcomitans serotype b bacteriophage capable of lysing bacteria within a biofilm.
机构信息
Laboratorio de Microbiología y Biotecnología Oral, Universidad Andres Bello, Echaurren 237, Santiago, Chile.
出版信息
Appl Environ Microbiol. 2011 May;77(9):3157-9. doi: 10.1128/AEM.02115-10. Epub 2011 Mar 4.
Abstract
A bacteriophage specific for Aggregatibacter actinomycetemcomitans serotype b, able to kill the bacterium within a biofilm, was isolated. Random mutagenesis of this phage rendered a bacteriophage able to kill 99% of the bacteria within a biofilm. This is the first report of a biocontrol experiment against A. actinomycetemcomitans.
摘要
分离到一株能特异性裂解伴放线放线杆菌 b 型的噬菌体，该噬菌体能在生物膜内杀死细菌。该噬菌体经随机突变后，能杀死生物膜内 99%的细菌。这是首次报道针对伴放线放线杆菌的生物防治实验。
相似文献
1
Isolation of a novel Aggregatibacter actinomycetemcomitans serotype b bacteriophage capable of lysing bacteria within a biofilm.分离一种新型伴放线放线杆菌 b 型噬菌体能在生物膜内裂解细菌。
Appl Environ Microbiol. 2011 May;77(9):3157-9. doi: 10.1128/AEM.02115-10. Epub 2011 Mar 4.
2
Prophage induction in lysogenic Aggregatibacter actinomycetemcomitans cells co-cultured with human gingival fibroblasts, and its effect on leukotoxin release.溶原性伴放线放线杆菌细胞与人类牙龈成纤维细胞共培养时的噬菌体诱导及其对白细胞毒素释放的影响。
Microb Pathog. 2013 Jan;54:54-9. doi: 10.1016/j.micpath.2012.09.005. Epub 2012 Sep 27.
3
Improving Phage-Biofilm In Vitro Experimentation.优化噬菌体-生物膜体外实验。
Viruses. 2021 Jun 19;13(6):1175. doi: 10.3390/v13061175.
4
Bacteriophage-Mediated Dispersal of Campylobacter jejuni Biofilms.噬菌体介导的空肠弯曲菌生物膜的传播。
Appl Environ Microbiol. 2011 May;77(10):3320-6. doi: 10.1128/AEM.02704-10. Epub 2011 Mar 25.
5
Biocontrol of Pectobacterium carotovorum subsp. carotovorum using bacteriophage PP1.利用噬菌体 PP1 防治胡萝卜软腐果胶杆菌亚种
J Microbiol Biotechnol. 2013 Aug;23(8):1147-53. doi: 10.4014/jmb.1304.04001.
6
Poly-N-acetylglucosamine mediates biofilm formation and detergent resistance in Aggregatibacter actinomycetemcomitans.聚-N-乙酰葡糖胺介导伴放线聚集杆菌生物膜的形成及对去污剂的抗性。
Microb Pathog. 2008 Jan;44(1):52-60. doi: 10.1016/j.micpath.2007.08.004. Epub 2007 Aug 12.
7
Developing a bacteriophage cocktail for biocontrol of potato bacterial wilt.开发一种噬菌体鸡尾酒来生物防治马铃薯青枯病。
Virol Sin. 2017 Dec;32(6):476-484. doi: 10.1007/s12250-017-3987-6. Epub 2017 Nov 16.
8
Isolation and Characterization of a Shewanella Phage-Host System from the Gut of the Tunicate, Ciona intestinalis.从被囊动物玻璃海鞘肠道中分离并鉴定希瓦氏菌噬菌体-宿主系统
Viruses. 2017 Mar 22;9(3):60. doi: 10.3390/v9030060.
9
Bacteriophage exploitation of bacterial biofilms: phage preference for less mature targets?噬菌体对细菌生物膜的利用：噬菌体是否偏好不太成熟的靶点？
FEMS Microbiol Lett. 2016 Feb;363(3). doi: 10.1093/femsle/fnv246. Epub 2016 Jan 6.
10
Bacteriophage therapy for membrane biofouling in membrane bioreactors and antibiotic-resistant bacterial biofilms.用于膜生物反应器中膜生物污染及抗生素抗性细菌生物膜的噬菌体疗法。
Biotechnol Bioeng. 2015 Aug;112(8):1644-54. doi: 10.1002/bit.25574. Epub 2015 Jun 15.
引用本文的文献
1
Bacteriophages as Targeted Therapeutic Vehicles: Challenges and Opportunities.作为靶向治疗载体的噬菌体：挑战与机遇
Bioengineering (Basel). 2025 Apr 29;12(5):469. doi: 10.3390/bioengineering12050469.
2
Phage therapy as an alternative strategy for oral bacterial infections: a systematic review.噬菌体疗法作为口腔细菌感染的替代策略：一项系统综述
BMC Oral Health. 2025 Jan 8;25(1):44. doi: 10.1186/s12903-024-05399-9.
3
Antibiofilm Effects of Modifying Polyvinylidene Fluoride Membranes with Polyethylenimine, Poly(acrylic acid) and Graphene Oxide.用聚乙烯亚胺、聚丙烯酸和氧化石墨烯改性聚偏氟乙烯膜的抗生物膜效果
Polymers (Basel). 2024 Dec 5;16(23):3418. doi: 10.3390/polym16233418.
4
Periodontitis: etiology, conventional treatments, and emerging bacteriophage and predatory bacteria therapies.牙周炎：病因、传统治疗方法以及新兴的噬菌体和捕食性细菌疗法。
Front Microbiol. 2024 Sep 26;15:1469414. doi: 10.3389/fmicb.2024.1469414. eCollection 2024.
5
Biological Traits and Comprehensive Genomic Analysis of Novel Bacteriophage EFP6.新型噬菌体EFP6的生物学特性及全基因组分析
Microorganisms. 2024 Jun 14;12(6):1202. doi: 10.3390/microorganisms12061202.
6
A review and new perspective on oral bacteriophages: manifestations in the ecology of oral diseases.口腔噬菌体综述及新视角：口腔疾病生态学中的表现
J Oral Microbiol. 2024 May 1;16(1):2344272. doi: 10.1080/20002297.2024.2344272. eCollection 2024.
7
Myriad applications of bacteriophages beyond phage therapy.噬菌体的除噬菌体治疗以外的多种应用。
PeerJ. 2023 Apr 21;11:e15272. doi: 10.7717/peerj.15272. eCollection 2023.
8
Current Status of Phage Therapy against Infectious Diseases and Potential Application beyond Infectious Diseases.噬菌体疗法对抗感染性疾病的现状及超越感染性疾病的潜在应用。
Int J Clin Pract. 2022 Oct 3;2022:4913146. doi: 10.1155/2022/4913146. eCollection 2022.
9
How Good are Bacteriophages as an Alternative Therapy to Mitigate Biofilms of Nosocomial Infections.噬菌体作为减轻医院感染生物膜的替代疗法效果如何。
Infect Drug Resist. 2022 Feb 17;15:503-532. doi: 10.2147/IDR.S348700. eCollection 2022.
10
Identification of Novel Bacteriophages with Therapeutic Potential That Target .鉴定具有治疗潜力的靶向. 的新型噬菌体
Infect Immun. 2019 Oct 18;87(11). doi: 10.1128/IAI.00512-19. Print 2019 Nov.
本文引用的文献
1
Isolation of a novel bacteriophage specific for the periodontal pathogen Fusobacterium nucleatum.分离一种新型噬菌体，特异性针对牙周病原菌核梭杆菌。
Appl Environ Microbiol. 2010 Nov;76(21):7243-50. doi: 10.1128/AEM.01135-10. Epub 2010 Sep 17.
2
Characterization of a new serotype g isolate of Aggregatibacter actinomycetemcomitans.一株新血清型 g 分离株伴放线放线杆菌的特性研究。
Mol Oral Microbiol. 2010 Jun;25(3):200-6. doi: 10.1111/j.2041-1014.2010.00572.x.
3
Genetic diversity and toxic activity of Aggregatibacter actinomycetemcomitans isolates.伴放线聚集杆菌分离株的遗传多样性和毒性活性
Oral Microbiol Immunol. 2009 Dec;24(6):493-501. doi: 10.1111/j.1399-302X.2009.00547.x.
4
Novel anti-microbial therapies for dental plaque-related diseases.用于治疗牙菌斑相关疾病的新型抗菌疗法。
Int J Antimicrob Agents. 2009 Jan;33(1):8-13. doi: 10.1016/j.ijantimicag.2008.07.014. Epub 2008 Sep 18.
5
Prevalence and distribution of principal periodontal pathogens worldwide.全球主要牙周病原体的患病率及分布情况。
J Clin Periodontol. 2008 Sep;35(8 Suppl):346-61. doi: 10.1111/j.1600-051X.2008.01280.x.
6
Periodontal diseases and health: Consensus Report of the Sixth European Workshop on Periodontology.牙周疾病与健康：第六届欧洲牙周病学研讨会共识报告
J Clin Periodontol. 2008 Sep;35(8 Suppl):333-7. doi: 10.1111/j.1600-051X.2008.01278.x.
7
Screen for leukotoxin mutants in Aggregatibacter actinomycetemcomitans: genes of the phosphotransferase system are required for leukotoxin biosynthesis.牙龈卟啉单胞菌中白细胞毒素突变体的筛选：磷酸转移酶系统的基因是白细胞毒素生物合成所必需的。
Infect Immun. 2008 Aug;76(8):3561-8. doi: 10.1128/IAI.01687-07. Epub 2008 Jun 9.
8
Aggregatibacter actinomycetemcomitans and its relationship to initiation of localized aggressive periodontitis: longitudinal cohort study of initially healthy adolescents.伴放线聚集杆菌及其与局限性侵袭性牙周炎发病的关系：对最初健康的青少年进行的纵向队列研究
J Clin Microbiol. 2007 Dec;45(12):3859-69. doi: 10.1128/JCM.00653-07. Epub 2007 Oct 17.
9
Antibiotic resistance in an in vitro subgingival biofilm model.体外龈下生物膜模型中的抗生素耐药性
Oral Microbiol Immunol. 2007 Oct;22(5):333-9. doi: 10.1111/j.1399-302X.2007.00366.x.
10
Systemic antibiotic therapy in the treatment of periodontitis.全身用抗生素治疗牙周炎。
J Can Dent Assoc. 2007 Jul-Aug;73(6):515-20.
Zotero 插件