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富血小板血浆疗法:系统文献回顾和临床应用证据。

Platelet-rich plasma therapy: a systematic literature review and evidence for clinical use.

机构信息

Department of Orthopaedic Surgery, Columbia University Medical Center, New York, NY, USA.

出版信息

Phys Sportsmed. 2011 Feb;39(1):42-51. doi: 10.3810/psm.2011.02.1861.

DOI:10.3810/psm.2011.02.1861
PMID:21378486
Abstract

Platelet-rich plasma (PRP) is an autologous blood-derived product with an increased concentration of platelets in plasma, which are used to deliver supraphysiological levels of growth factors. Platelet-rich plasma has been used in many fields, including oral, maxillofacial, and plastic surgery. Its use in sports medicine has been increasing after recent evidence and media publicity suggest that it may augment the treatment of muscle strains, as well as tendon and ligament healing. Basic science and animal studies show promising results, but high-level clinical trials have yet to prove its efficacy. With increasing media coverage on the use of PRP in athletes, it is paramount that orthopedic surgeons and sports medicine physicians understand the various methods of preparation and administration, potential clinical applications, and available clinical results to best counsel patients on its advantages and disadvantages.

摘要

富血小板血浆(PRP)是一种自体血液衍生产品,其中血浆中的血小板浓度增加,用于输送超生理水平的生长因子。PRP 已被广泛应用于口腔、颌面和整形外科学等多个领域。最近的证据和媒体宣传表明,PRP 可能会增强肌肉拉伤以及肌腱和韧带愈合的治疗效果,因此其在运动医学中的应用也在不断增加。基础科学和动物研究显示出有前景的结果,但高级别的临床试验尚未证明其疗效。随着媒体对运动员使用 PRP 的报道不断增加,骨科医生和运动医学医生了解其各种制备和管理方法、潜在的临床应用以及现有的临床结果至关重要,以便就其优缺点为患者提供最佳建议。

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