Department of Polymer Materials and Engineering, South China University of Technology, Guangzhou 510640, China.
Biomacromolecules. 2011 Apr 11;12(4):1312-21. doi: 10.1021/bm2000378. Epub 2011 Mar 23.
From the point of better biocompatibility and sustainability, biobased shape memory polymers (SMPs) are highly desired. We used 1,3-propanediol, sebacic acid, and itaconic acid, which have been industrially produced via fermentation or extraction with large quantities as the main raw materials for the synthesis of biobased poly(propylene sebacate). Diethylene glycol was used to tailor the flexibility of the polyester. The resulted polyesters were found to be promising SMPs with excellent shape recovery and fixity (near 100% and independent of thermomechanical cycles). The switching temperature and recovery speed of the SMPs are tunable by controlling the composition of the polyesters and their curing extent. The continuously changed switching temperature ranging from 12 to 54 °C was realized. Such temperature range is typical for biomedical applications in the human body. The molecular and crystalline structures were explored to correlate to the shape memory behavior. The combination of potential biocompatibility and biodegradability of the biobased SMPs makes them suitable for fabricating biomedical devices.
从更好的生物相容性和可持续性的角度来看，生物基形状记忆聚合物（SMP）是非常理想的。我们使用了经过发酵或提取大量生产的 1,3-丙二醇、癸二酸和衣康酸作为合成生物基聚（丙二酸癸酯）的主要原料。二甘醇用于调整聚酯的柔韧性。结果表明，这些聚酯是具有良好形状回复和固定性能（接近 100%，且与热机械循环无关）的有前途的 SMP。通过控制聚酯的组成及其固化程度，可以调节 SMP 的切换温度和回复速度。实现了从 12 到 54°C 的连续变化切换温度。这种温度范围是人体中生物医学应用的典型范围。还探索了分子和晶体结构，以与形状记忆行为相关联。生物基 SMP 的潜在生物相容性和可生物降解性的结合使它们适合制造生物医学设备。
