Chouinard Laura E
Department of Family Relations and Applied Nutrition, University of Guelph, ON, Canada.
Can J Diet Pract Res. 2011 Spring;72(1):e107-14. doi: 10.3148/72.1.2011.48.
North American family physicians and dietitians commonly recommend psyllium fibre supplementation for treating symptoms of irritable bowel syndrome (IBS). In this review, evidence on the effectiveness of psyllium supplementation for diagnosed IBS symptoms was evaluated and summarized. A systematic search of MEDLINE, CINAHL, and Web of Science was conducted. Included were full-length, peer-reviewed, English-language articles in which psyllium ingestion was tested for its effect on IBS symptoms. Quality of these articles also was assessed. Twelve met the criteria for complete data abstraction. Seventy-five percent of the studies examined were of weak quality. Study designs and methods were heterogeneous. Patient-perceived global symptoms improved significantly in six of the nine studies measuring a global symptom outcome. In one study, significant improvements occurred in reported abdominal pain; in three, improvement did not occur. Quality of life and flatulence did not improve significantly in any studies in which these outcomes were examined. The results of this systematic review indicate limited and conflicting evidence to support the recommendation of psyllium supplementation for symptomatic IBS treatment.
北美家庭医生和营养师通常推荐补充车前草纤维来治疗肠易激综合征（IBS）的症状。在本综述中，对补充车前草治疗已确诊IBS症状的有效性证据进行了评估和总结。对MEDLINE、CINAHL和科学网进行了系统检索。纳入的是经同行评审的英文全文文章，其中测试了摄入车前草对IBS症状的影响。还评估了这些文章的质量。12篇文章符合完整数据提取的标准。所审查的研究中有75%质量较弱。研究设计和方法各不相同。在九项测量总体症状结果的研究中，有六项研究显示患者感知的总体症状有显著改善。在一项研究中，报告的腹痛有显著改善；在三项研究中则未出现改善。在任何检查这些结果的研究中，生活质量和气胀均未显著改善。本系统综述的结果表明，支持推荐补充车前草治疗有症状IBS的证据有限且相互矛盾。
