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[心肌梗死患者及其近亲中的低高密度脂蛋白胆固醇]

[Low HDL cholesterol in close relatives and patients with myocardial infarct].

作者信息

Pometta D, Micheli H, Jornot C, Scherrer J R

出版信息

Schweiz Med Wochenschr. 1978 Dec 2;108(48):1888-91.

PMID:213831
Abstract

Male patients aged 40 to 59 who had had acute myocardial infarction three months previously displayed a lower HDL cholesterol than the HDL cholesterol of an apparently healthy control group. The male first degree relatives of patients with acute myocardial infarction, like the patients with coronary disease, had a low HDL cholesterol which differed significantly from the HDL cholesterol of the control group. Low HDL cholesterol appears to be a better "marker" of patients with coronary disease and relatives of patients with acute myocardial infarction than serum cholesterol and triglycerides. The importance of low HDL' cholesterol could be related to the role of HDL in the cholesterol transport system from the peripheral tissues.

摘要

三个月前发生过急性心肌梗死的40至59岁男性患者,其高密度脂蛋白胆固醇水平低于明显健康的对照组。急性心肌梗死患者的男性一级亲属,与冠心病患者一样,高密度脂蛋白胆固醇水平较低,与对照组的高密度脂蛋白胆固醇水平有显著差异。与血清胆固醇和甘油三酯相比,低高密度脂蛋白胆固醇似乎是冠心病患者和急性心肌梗死患者亲属更好的“标志物”。低高密度脂蛋白胆固醇的重要性可能与高密度脂蛋白在胆固醇从外周组织转运系统中的作用有关。

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