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Activation of alternative pathways of angiogenesis and involvement of stem cells following anti-angiogenesis treatment in glioma.抗血管生成治疗后胶质瘤中血管生成的替代途径的激活和干细胞的参与。
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本文引用的文献

1
Transdifferentiation of glioblastoma cells into vascular endothelial cells.胶质母细胞瘤细胞向血管内皮细胞的转分化。
Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4274-80. doi: 10.1073/pnas.1016030108. Epub 2011 Jan 24.
2
Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells.通过神经胶质瘤干细胞样细胞的内皮分化实现肿瘤血管生成。
Nature. 2010 Dec 9;468(7325):824-8. doi: 10.1038/nature09557. Epub 2010 Nov 21.
3
Glioblastoma stem-like cells give rise to tumour endothelium.胶质母细胞瘤干细胞可产生肿瘤内皮细胞。
Nature. 2010 Dec 9;468(7325):829-33. doi: 10.1038/nature09624. Epub 2010 Nov 21.
4
A new alternative mechanism in glioblastoma vascularization: tubular vasculogenic mimicry.胶质母细胞瘤血管生成的新替代机制：管状血管生成拟态。
Brain. 2010 Apr;133(Pt 4):973-82. doi: 10.1093/brain/awq044.
5
Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors.血管生态位通过血管生成因子在促进肿瘤生长和组织修复中的指导作用。
Nat Rev Cancer. 2010 Feb;10(2):138-46. doi: 10.1038/nrc2791.
6
Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells.造血的植入和重建依赖于VEGFR2介导的窦状内皮细胞再生。
Cell Stem Cell. 2009 Mar 6;4(3):263-74. doi: 10.1016/j.stem.2009.01.006.
7
Development of a novel mouse glioma model using lentiviral vectors.利用慢病毒载体构建新型小鼠胶质瘤模型
Nat Med. 2009 Jan;15(1):110-6. doi: 10.1038/nm.1863. Epub 2009 Jan 4.
8
Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma.复发性胶质母细胞瘤中，先使用单药贝伐单抗，肿瘤进展时再使用贝伐单抗联合伊立替康的II期试验。
J Clin Oncol. 2009 Feb 10;27(5):740-5. doi: 10.1200/JCO.2008.16.3055. Epub 2008 Dec 29.
9
Refractoriness to antivascular endothelial growth factor treatment: role of myeloid cells.抗血管内皮生长因子治疗的耐药性：髓样细胞的作用
Cancer Res. 2008 Jul 15;68(14):5501-4. doi: 10.1158/0008-5472.CAN-08-0925.
10
Cancer. A few to flip the angiogenic switch.癌症。少数情况会激活血管生成开关。
Science. 2008 Jan 11;319(5860):163-4. doi: 10.1126/science.1153615.

A target for antiangiogenic therapy: vascular endothelium derived from glioblastoma.

作者信息

Hormigo Adília, Ding Bi-Sen, Rafii Shahin

机构信息

Department of Genetic Medicine, Howard Hughes Medical Institute, Ansary Stem Cell Institute, Weill Cornell Medical College, New York, NY 10021, USA.

出版信息

Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4271-2. doi: 10.1073/pnas.1019656108. Epub 2011 Mar 7.

DOI:10.1073/pnas.1019656108
PMID:21383166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3060236/
Abstract
摘要