Rice Quantum Institute, Rice University, 6100 Main St., Houston, TX 77005, USA. Medical Scientist Training Program, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.
J Breath Res. 2007 Sep;1(1):014001. doi: 10.1088/1752-7155/1/1/014001. Epub 2007 Jul 11.
Laser absorption spectroscopy (LAS) in the mid-infrared region offers a promising new effective technique for the quantitative analysis of trace gases in human breath. LAS enables sensitive, selective detection, quantification and monitoring in real time, of gases present in breath. This review summarizes some of the recent advances in LAS based on semiconductor lasers and optical detection techniques for clinically relevant exhaled gas analysis in breath, specifically such molecular biomarkers as nitric oxide, ammonia, carbon monoxide, ethane, carbonyl sulfide, formaldehyde and acetone.
激光吸收光谱（LAS）在中红外区域为痕量气体的定量分析提供了一种很有前途的新方法。LAS 可以实时进行敏感、选择性检测、定量和监测，检测呼吸气中存在的气体。本文综述了基于半导体激光器和光学检测技术的 LAS 在呼吸中临床相关呼气分析方面的一些最新进展，特别是一些分子生物标志物，如一氧化氮、氨、一氧化碳、乙烷、羰基硫、甲醛和丙酮。
