Department of Pharmacy Practice and Science, University of Arizona, Tucson, USA.
Exerc Sport Sci Rev. 2011 Jul;39(3):155-60. doi: 10.1097/JES.0b013e3182172a5a.
Exercise activates adrenergic and purinergic pathways that regulate activity of ion channels on airway epithelia cells and sweat glands. Therefore, we hypothesize that exercise is not only an important therapy for cystic fibrosis (CF) patients by facilitating systemic improvements but, more importantly, that exercise can improve the pathophysiological ion dysregulation at a cellular level, thereby enhancing quality of life in CF.
运动激活了调节气道上皮细胞和汗腺离子通道活性的肾上腺素能和嘌呤能途径。因此，我们假设运动不仅通过促进全身改善是囊性纤维化 (CF) 患者的重要治疗方法，而且更重要的是，运动可以改善细胞水平的病理生理离子失调，从而提高 CF 患者的生活质量。
