Laboratory of Bioimaging Probe Development, Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore 138667, Singapore.
Chem Commun (Camb). 2011 Apr 21;47(15):4508-10. doi: 10.1039/c1cc10362h. Epub 2011 Mar 8.
A bodipy probe was developed for site-specific labeling of tagged proteins inside live cells which displays a large spectral change upon covalent coupling to the designed peptide that contains two pairs of Arg-Cys.
开发了一种用于在活细胞内对标记蛋白进行特异性标记的 Bodipy 探针,当与包含两对 Arg-Cys 的设计肽共价偶联时,该探针显示出很大的光谱变化。