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基于 BODIPY-DCDHF 缀合物的比率荧光探针用于活细胞中次氯酸的检测。

A ratiometric fluorescent probe based on a BODIPY-DCDHF conjugate for the detection of hypochlorous acid in living cells.

机构信息

Department of Chemistry, Institute of Nanosensor and Biotechnology, Dankook University, 126 Jukjeon-dong, Yongin-si, Gyeonggi-do, 448-701, Korea.

出版信息

Analyst. 2013 Jun 21;138(12):3368-71. doi: 10.1039/c3an36820c. Epub 2013 Apr 30.

DOI:10.1039/c3an36820c
PMID:23629010
Abstract

A colorimetric and ratiometric fluorescent probe consisting of a boron-dipyrromethene (BODIPY) dye conjugated with a 2-dicyanomethylene-3-cyano-2,5-dihydrofuran (DCDHF) group has been designed for the selective and sensitive detection of HOCl/OCl(-)via oxidative cleavage of an alkene linker between BODIPY and DCDHF.

摘要

一种由硼二吡咯甲川（BODIPY）染料与 2-二氰基亚甲基-3-氰基-2,5-二氢呋喃（DCDHF）基团共轭而成的比色和比率荧光探针，已被设计用于通过 BODIPY 和 DCDHF 之间的烯烃键的氧化裂解，选择性和灵敏地检测 HOCl/OCl(-)。

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