Remy C
Centre médical de la Teppe, Tain L'Hermitage.
Presse Med. 1990 Mar 24;19(11):511-3.
A multicentre open therapeutic trial comparing carbamazepine with slow-release carbamazepine was conducted in 114 epileptic patients older than 12 years. The patients received the two products successively during two periods of 1 month each. With slow-release carbamazepine the number of doses could be reduced to 2 per day without decrease in effectiveness and with less side-effects. The twice-a-day dosage should result in better compliance and consequently in a better quality of treatment in the long term.
一项针对114名12岁以上癫痫患者的多中心开放性治疗试验，比较了卡马西平与缓释卡马西平。患者在两个为期1个月的时间段内先后服用这两种药物。使用缓释卡马西平，每日剂量可减至2次，而疗效不减且副作用更少。每日两次的给药方案应能提高依从性，从而从长远来看提高治疗质量。
