Uetama Toshifumi, Yoshida Hiroshi, Hirakata Atsushi, Yokoyama Tadashi, Maruyama Hiroshi, Suzuki Seiji, Matsutani Takeshi, Matsushita Akira, Sasajima Koji, Uchida Eiji
Surgery for Organ Function and Biological Regulation, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
J Nippon Med Sch. 2011;78(1):34-9. doi: 10.1272/jnms.78.34.
We describe a patient with symptomatic giant hepatic hemangioma treated with hepatectomy. A 53-year-old woman presented with upper abdominal distension and appetite loss. The medical history included multiple hepatic hemangiomas that had been detected 2 years earlier but were left untreated. Initial laboratory tests revealed pancytopenia and mild coagulopathy. Computed tomography and magnetic resonance imaging demonstrated a giant hemangioma, 27 cm in diameter, in the enlarged right lobe of the liver. The inferior vena cava was compressed by tumor without thrombus in the infrahepatic vena cava. The portal venous phase of supramesenteric arteriography revealed compression of the portal vein. There were several hemangiomas in the left lobe. Gastric outlet obstruction due to giant hepatic hemangioma in the right lobe was diagnosed. Laparotomy was performed, and a markedly enlarged liver was detected. Right hepatectomy was performed with an anterior approach. The liver-hanging maneuver could not be performed because of tumor compression of the inferior vena cava. Right hepatectomy was performed with intermittent clamping (Pringle maneuver). Hepatic hemangiomas of the left lobe were not resected because the remnant liver would be reduced. The weight of the resected specimen was 2,100 g. Pathologic examination of the surgical specimen confirmed the presence of benign hepatic hemangiomas. The postoperative course was uneventful, and the patient's appetite improved. The patient was discharged 8 days after the operation. Abdominal distension decreased and laboratory data improved after the operation. Computed tomography revealed hypertrophy of the left lobe of the liver after the operation.
我们描述了一例接受肝切除术治疗的有症状巨大肝血管瘤患者。一名53岁女性出现上腹部胀满和食欲减退。病史包括2年前检测出的多发肝血管瘤,但未予治疗。初始实验室检查显示全血细胞减少和轻度凝血功能障碍。计算机断层扫描和磁共振成像显示肝脏右叶增大,有一个直径27 cm的巨大血管瘤。下腔静脉受压,肝下腔静脉无血栓形成。肠系膜上动脉造影门静脉期显示门静脉受压。左叶有多个血管瘤。诊断为右叶巨大肝血管瘤导致胃出口梗阻。行剖腹手术,发现肝脏明显增大。采用前路行右肝切除术。由于下腔静脉受肿瘤压迫,无法进行肝脏悬吊术。采用间歇性阻断(普林格尔手法)行右肝切除术。由于剩余肝脏体积会减小,未切除左叶肝血管瘤。切除标本重量为2100 g。手术标本的病理检查证实为良性肝血管瘤。术后过程顺利,患者食欲改善。患者术后8天出院。术后腹胀减轻,实验室数据改善。计算机断层扫描显示术后肝脏左叶肥大。