Sliem Hamdy, Nasr Gamela, Ibrahiem Dalia
Hamdy Sliem, Department of Internal Medicine, Faculty of Medicine, Suez Canal University, 41522 Ismailia, Egypt.
World J Cardiol. 2011 Feb 26;3(2):48-53. doi: 10.4330/wjc.v3.i2.48.
To evaluate the left ventricular structure and function in isolated metabolic syndrome.
One hundred and fifty six consecutive adults with metabolic syndrome were enrolled in the study. Fifty nine had isolated metabolic syndrome (group A) and 97 had metabolic syndrome with hypertension and/or diabetes (group B). There was a control group of 34 healthy adults. In addition to classic echocardiographic assessment of myocardial structural and functional changes, the Tei index was used to evaluate global left ventricular performance.
There were no statistically significant differences between group A and controls in all parameters of left ventricular structural, systolic, and diastolic function except global myocardial performance (Tei index). On the other hand, significant differences were observed between group B and the control group in most of the parameters of left ventricular structural and global performance.
The early identification of isolated metabolic syndrome in non-diabetic, non-hypertensive adults may be an indication that aggressive preventive measures should not be postponed until overt obesity, hypertension or diabetes mellitus has developed.
评估单纯代谢综合征患者的左心室结构和功能。
连续纳入156例成年代谢综合征患者进行研究。其中59例为单纯代谢综合征患者（A组），97例为合并高血压和/或糖尿病的代谢综合征患者（B组）。另有34例健康成年人为对照组。除了对心肌结构和功能变化进行经典的超声心动图评估外，还使用Tei指数评估左心室整体功能。
除整体心肌功能（Tei指数）外，A组与对照组在左心室结构、收缩和舒张功能的所有参数上均无统计学显著差异。另一方面，B组与对照组在左心室结构和整体功能的大多数参数上存在显著差异。
在非糖尿病、非高血压的成年人中早期识别单纯代谢综合征可能表明，积极的预防措施不应推迟到明显肥胖、高血压或糖尿病出现之后。
