Department of Pediatrics, SDM College of Medical Sciences and Hospital, Sattur, Dharwad, Karnataka 580009, India.
Indian J Pediatr. 2011 Oct;78(10):1284-6. doi: 10.1007/s12098-011-0393-1. Epub 2011 Mar 9.
Hemoglobin-J is a rare hemoglobin variant known to be clinically silent most of the times, only to be detected accidentally. Herein, the authors report a case of Hemoglobin-J manifesting as unstable hemoglobin detected during evaluation of hemolytic anemia in an 8 month-old-infant. Cation Exchange-High Performance Liquid Chromatography(CE-HPLC) was used to identify this variant after Hb electrophoresis was reported to be normal.
血红蛋白-J 是一种罕见的血红蛋白变体，大多数情况下临床无症状，仅偶然被发现。本文报道了一例血红蛋白-J 病例，该患者为 8 月龄婴儿，因溶血性贫血评估时发现不稳定血红蛋白。Hb 电泳报告正常后，使用阳离子交换-高效液相色谱（CE-HPLC）来鉴定该变体。
