血红蛋白 J--导致先天性溶血性贫血。
Hemoglobin J--as a cause of congenital hemolytic anemia.
机构信息
Department of Pediatrics, SDM College of Medical Sciences and Hospital, Sattur, Dharwad, Karnataka 580009, India.
出版信息
Indian J Pediatr. 2011 Oct;78(10):1284-6. doi: 10.1007/s12098-011-0393-1. Epub 2011 Mar 9.
PMID:21390522
Abstract
Hemoglobin-J is a rare hemoglobin variant known to be clinically silent most of the times, only to be detected accidentally. Herein, the authors report a case of Hemoglobin-J manifesting as unstable hemoglobin detected during evaluation of hemolytic anemia in an 8 month-old-infant. Cation Exchange-High Performance Liquid Chromatography(CE-HPLC) was used to identify this variant after Hb electrophoresis was reported to be normal.
摘要
血红蛋白-J 是一种罕见的血红蛋白变体，大多数情况下临床无症状，仅偶然被发现。本文报道了一例血红蛋白-J 病例，该患者为 8 月龄婴儿，因溶血性贫血评估时发现不稳定血红蛋白。Hb 电泳报告正常后，使用阳离子交换-高效液相色谱（CE-HPLC）来鉴定该变体。
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Indian J Pediatr. 2011 Oct;78(10):1284-6. doi: 10.1007/s12098-011-0393-1. Epub 2011 Mar 9.
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本文引用的文献
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A diabetic case with hemoglobin J-Meerut and low HbA1C levels.一例伴有血红蛋白J-密拉特且糖化血红蛋白水平较低的糖尿病病例。
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