Selvakumar C J, Justin C, Gnaneswaran T R, Chandrasekaran M
Dept. of Neurology, Govt. Rajaji Hospital, Madurai.
J Assoc Physicians India. 2010 Sep;58:572-4.
Varicella zoster vasculopathy is a rare complication of chicken pox. Varicella cerebellitis, a post or para-infectious condition, is a common sequelae of chicken pox. Varicella angiopathy presents as acute hemiparesis, aphasia, hemianaesthesia or other focal neurologic or retinal deficits associated with mononuclear pleocytosis and VZV specific antibodies in CSF. Varicella angiopathy affecting the posterior circulation is very rare. We report a 15 yr old boy with progressive neurologic deficits over a month following a chicken pox 3 months prior to the onset of symptoms. On investigation he had infarcts both in the anterior and posterior circulation territories in CT and MRI with mononuclear pleocytosis in CSF elevated IgG and IgM in CSF. He was treated with intravenous acyclovir and corticosteroids.
水痘带状疱疹血管病变是水痘的一种罕见并发症。水痘后脑炎是一种感染后或感染旁的病症,是水痘常见的后遗症。水痘血管病变表现为急性偏瘫、失语、偏身感觉缺失或其他局灶性神经或视网膜缺陷,伴有脑脊液单核细胞增多和脑脊液中VZV特异性抗体。影响后循环的水痘血管病变非常罕见。我们报告一名15岁男孩,在症状出现前3个月患水痘后,在一个月内出现进行性神经功能缺损。经检查,他的CT和MRI显示前循环和后循环区域均有梗死灶,脑脊液单核细胞增多,脑脊液中IgG和IgM升高。他接受了静脉注射阿昔洛韦和皮质类固醇治疗。