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本文引用的文献

1
Epidemiology of antituberculosis drug resistance 2002-07: an updated analysis of the Global Project on Anti-Tuberculosis Drug Resistance Surveillance.2002 - 2007年抗结核药物耐药性流行病学：全球抗结核药物耐药性监测项目的最新分析
Lancet. 2009 May 30;373(9678):1861-73. doi: 10.1016/S0140-6736(09)60331-7. Epub 2009 Apr 15.
2
Transmission of MDR and XDR tuberculosis in Shanghai, China.中国上海耐多药和广泛耐药结核病的传播
PLoS One. 2009;4(2):e4370. doi: 10.1371/journal.pone.0004370. Epub 2009 Feb 3.
3
Characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates in China.中国广泛耐药结核分枝杆菌临床分离株的特征分析
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4
Worldwide emergence of extensively drug-resistant tuberculosis.广泛耐药结核病在全球范围内的出现。
Emerg Infect Dis. 2007 Mar;13(3):380-7. doi: 10.3201/eid1303.061400.
5
XDR tuberculosis--implications for global public health.广泛耐药结核病——对全球公共卫生的影响
N Engl J Med. 2007 Feb 15;356(7):656-9. doi: 10.1056/NEJMp068273.
6
Drug-susceptibility testing in tuberculosis: methods and reliability of results.结核病的药敏试验：方法及结果的可靠性
Eur Respir J. 2005 Mar;25(3):564-9. doi: 10.1183/09031936.05.00111304.
7
Is second-line anti-tuberculosis drug susceptibility testing reliable?二线抗结核药物敏感性检测可靠吗？
Int J Tuberc Lung Dis. 2004 Sep;8(9):1157-8.

基于实验室的广泛耐药结核病监测，中国。

Laboratory-based surveillance of extensively drug-resistant tuberculosis, China.

机构信息

Shandong Provincial Chest Hospital, Jinan, People's Republic of China.

出版信息

Emerg Infect Dis. 2011 Mar;17(3):495-7. doi: 10.3201/eid1703.100812.

DOI:10.3201/eid1703.100812
PMID:21392442
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3165999/
Abstract

To estimate the prevalence of extensively drug-resistant tuberculosis (XDR TB) in China, we retrospectively analyzed drug-resistance profiles of 989 clinical Mycobacterium tuberculosis isolates. We found 319 (32.3%) isolates resistant to ≥1 first-line drugs; 107 (10.8%) isolates were multidrug resistant, of which 20 (18.7%) were XDR. XDR TB is of major concern in China.

摘要

为了估计中国广泛耐药结核病（XDR-TB）的流行率，我们回顾性分析了 989 株临床分枝杆菌结核分离株的耐药谱。我们发现 319 株（32.3%）分离株对至少 1 种一线药物耐药；107 株（10.8%）分离株为耐多药，其中 20 株（18.7%）为 XDR。XDR-TB 在中国受到高度关注。