Tugela Ferry Care and Research Collaboration, Tugela Ferry, South Africa.
Emerg Infect Dis. 2011 Mar;17(3):510-3. doi: 10.3201/eid1703.101363.
We expanded second-line tuberculosis (TB) drug susceptibility testing for extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa. Of 19 patients with extensively drug-resistant TB identified during February 2008-April 2009, 13 (68%) had isolates resistant to all 8 drugs tested. This resistance leaves no effective treatment with available drugs in South Africa.
我们扩大了南非广泛耐药结核分枝杆菌分离株二线抗结核药物敏感性检测。在 2008 年 2 月至 2009 年 4 月期间发现的 19 例广泛耐药结核患者中,有 13 例(68%)的分离株对所有 8 种测试药物均耐药。这种耐药性使得南非现有的药物治疗无效。