[不寻常的视网膜异常：与坏血病相关的视网膜出血]

[Unusual retinal abnormality: retinal hemorrhages related to scurvy].

作者信息

Errera M-H, Dupas B, Man H, Gualino V, Gaudric A, Massin P

机构信息

Service d'ophtalmologie, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, université Paris-VII, 2, rue Ambroise-Paré, 75010 Paris, France.

出版信息

J Fr Ophtalmol. 2011 Mar;34(3):186.e1-3. doi: 10.1016/j.jfo.2010.10.018.

DOI:10.1016/j.jfo.2010.10.018

PMID:21392843

Abstract

A diet restricted to rice and boiled fruit and vegetables leads to vitamin C deficiency. We describe the third case, to our knowledge, of retinal hemorrhages related to scurvy. Reduced bilateral visual acuity in a 50-year-old patient was associated with macrocytic anemia, denutrition, and cutaneous ecchymoses. Oral vitamin C treatment provided subjective clinical improvement and regression of the retinal hemorrhages on fundus examination, with no side effects. Vitamin C plays an important role in collagen stability in vascular and bone walls.

摘要

仅限于大米、水煮水果和蔬菜的饮食会导致维生素C缺乏。据我们所知，我们描述了第三例与坏血病相关的视网膜出血病例。一名50岁患者双侧视力下降，伴有巨幼细胞贫血、营养不良和皮肤瘀斑。口服维生素C治疗使临床症状主观上得到改善，眼底检查显示视网膜出血消退，且无副作用。维生素C在血管壁和骨壁的胶原蛋白稳定性中起重要作用。