Department of Medical Microbiology and Infection Control, VU University Medical Center, 1007 MB Amsterdam, The Netherlands.
Diagn Microbiol Infect Dis. 2011 May;70(1):142-4. doi: 10.1016/j.diagmicrobio.2010.11.016. Epub 2011 Mar 9.
We describe a case of a total hip arthroplasty infection caused by Abiotrophia defectiva, identified by 16S rRNA gene sequencing. Removal of the prosthesis followed by antibiotic treatment resulted in a good clinical outcome. 16S rRNA gene sequencing can be a useful tool in diagnosing infection with this fastidious microorganism that can easily be misidentified using phenotypic identification methods.
我们描述了一例由 16S rRNA 基因测序鉴定的缺陷嗜氧菌引起的全髋关节置换术后感染。取出假体后进行抗生素治疗,取得了良好的临床效果。16S rRNA 基因测序可作为一种有用的工具,用于诊断这种难以培养的微生物感染,使用表型鉴定方法可能容易导致误诊。