Department of Radiology, Seoul National University College of Medicine, Korea.
AJNR Am J Neuroradiol. 2011 May;32(5):917-22. doi: 10.3174/ajnr.A2411. Epub 2011 Mar 10.
The microcatheter protective technique positions an additional microcatheter in the parent or side-branching artery to protect it during coil embolization. The purpose of this study was to describe this method and to evaluate its efficacy and safety as an alternative to a multiple-microcatheter or balloon- or stent-assisted technique for wide-neck aneurysms.
A retrospective review of 74 patients (43 women; mean age, 59.6 years) with 75 wide-neck aneurysms treated with the microcatheter protective technique between January 2003 and April 2010 was performed. Immediate postembolization angiograms were evaluated by using a conventional angiographic scale, and clinical evaluation was performed by using the GOS. Clinical and imaging follow-up were available in 57 (76%) patients, with a mean of 14.7 months.
Postembolization angiograms demonstrated total occlusion in 45 of 75 (60%) aneurysms, a neck remnant in 17 (22.7%), and body filling in 13 (17.3%). The technique-related complication rate was 17.4% (13/75), and the procedural-related morbidity rate was 1.3% (1/74). All patients, except 3 complicated cases with a GOS of <4, had a GOS of 5 at the end of the study period. Of the 57 aneurysms with follow-up, recanalization developed in 5 (8.8%) aneurysms, and 3 (5.3%) cases of major recanalization were re-treated endovascularly.
The microcatheter protective technique is feasible and safe for coil embolization of wide-neck aneurysms, especially in cases that are not suitable for multiple catheter or balloon- or stent-assisted techniques.
微导管保护技术是指在进行线圈栓塞时,将额外的微导管置于母血管或分支血管内以保护其不受损伤。本研究旨在描述这种方法,并评估其作为一种替代多种微导管、球囊或支架辅助技术治疗宽颈动脉瘤的疗效和安全性。
回顾性分析 2003 年 1 月至 2010 年 4 月期间采用微导管保护技术治疗的 74 例(43 例女性;平均年龄 59.6 岁)75 个宽颈动脉瘤患者的临床资料。采用传统血管造影标准评估即刻栓塞后血管造影结果,采用 GOS 进行临床评估。57 例(76%)患者获得了临床和影像学随访,平均随访时间为 14.7 个月。
栓塞后血管造影显示,45 个(60%)动脉瘤完全闭塞,17 个(22.7%)瘤颈残留,13 个(17.3%)瘤体显影。技术相关并发症发生率为 17.4%(13/75),手术相关发病率为 1.3%(1/74)。除 3 例 GOS<4 的复杂病例外,所有患者在研究结束时的 GOS 均为 5。57 个有随访的动脉瘤中,5 个(8.8%)发生再通,3 个(5.3%)严重再通的病例再次行血管内治疗。
微导管保护技术对于宽颈动脉瘤的线圈栓塞是可行且安全的,特别是对于不适合使用多种导管、球囊或支架辅助技术的病例。