Yoon Pyeong-Ho, Lee Jae-Wook, Lee Yun-Ho, Kwon Young-Sub, Yang Kook-Hee
1 Department of Radiology, Ilsan Hospital, National Health Insurance Service, South Korea.
2 Department of Neurosurgery, Ilsan Hospital, National Health Insurance Service, South Korea.
Interv Neuroradiol. 2017 Oct;23(5):477-484. doi: 10.1177/1591019917708570. Epub 2017 May 22.
The dual microcatheter technique is an alternative treatment for stent-assisted coiling in acutely ruptured wide-necked aneurysms because of no antiplatelet therapy. We assessed the safety and efficacy of this technique in ruptured wide-necked aneurysms. Between March 2008 and March 2016, 56 acutely ruptured aneurysms were treated with the dual microcatheter technique. The angiographic results, treatment-related complications, and clinical outcome were documented. Angiographic follow-up was available in 37 patients at a mean of 20.6 months (6 to 81 months). On the postembolization angiograms, 27 (48.2%) aneurysms showed complete occlusion (Raymond 1), 15 (26.8%) showed neck remnant (Raymond 2), and 14 (25.0%) showed body remnant (Raymond 3). Treatment-related complications occurred in seven patients (12.5%) and six patients remained asymptomatic. The permanent complication rate was 1.8% (1/56). A good outcome (modified Rankin Scale (mRS) score, 0-2) was observed in 64.3% of patients at the time of discharge. Five patients had died, all of the sequelae of subarachnoid hemorrhage. The overall mortality rate was 8.9% (5/56); however, the treatment-related mortality rate was 0%. Of the 37 aneurysms for which angiographic follow-up was available, 21 (56.8%) aneurysms demonstrated recanalization. Five aneurysms with recanalization were retreated endovascularly. There was one aneurysm re-rupture on follow-up and it rebled 21 months after the initial procedure. The dual microcatheter technique is a safe and effective treatment for acutely ruptured wide-necked aneurysms due to low treatment-related complication and mortality rate. However, the high rate of postembolization incomplete occlusion and recanalization remains as the main challenge.
双微导管技术是急性破裂宽颈动脉瘤支架辅助弹簧圈栓塞术的一种替代治疗方法,因为无需抗血小板治疗。我们评估了该技术在破裂宽颈动脉瘤治疗中的安全性和有效性。2008年3月至2016年3月期间,56例急性破裂动脉瘤采用双微导管技术进行治疗。记录血管造影结果、治疗相关并发症及临床结局。37例患者获得血管造影随访,平均随访时间为20.6个月(6至81个月)。栓塞术后血管造影显示,27例(48.2%)动脉瘤完全闭塞(Raymond 1级),15例(26.8%)显示瘤颈残留(Raymond 2级),14例(25.0%)显示瘤体残留(Raymond 3级)。7例患者(12.5%)发生治疗相关并发症,6例患者无症状。永久性并发症发生率为1.8%(1/56)。出院时64.3%的患者预后良好(改良Rankin量表(mRS)评分,0 - 2分)。5例患者死亡,均死于蛛网膜下腔出血后遗症。总死亡率为8.9%(5/56);然而,治疗相关死亡率为0%。在37例有血管造影随访的动脉瘤中,21例(56.8%)出现再通。5例再通的动脉瘤接受了血管内再次治疗。随访中有1例动脉瘤再破裂,在初次手术后21个月再次出血。双微导管技术治疗急性破裂宽颈动脉瘤安全有效,治疗相关并发症和死亡率较低。然而,栓塞术后不完全闭塞和再通率较高仍是主要挑战。