Department of Ophthalmology and Visual Sciences, W.K. Kellogg Eye Center, MI, USA.
AJNR Am J Neuroradiol. 2011 Dec;32(11):E203-5. doi: 10.3174/ajnr.A2435. Epub 2011 Mar 10.
In accelerated hypertension, vasogenic brain edema associated with PRES may represent either autoregulatory breakthrough leading to vasodilation or excessive autoregulation leading to vasoconstriction. We describe 2 patients with PRES in accelerated hypertension who had serous retinal detachments, a vasoconstrictive phenomenon. The concurrence of serous retinal detachment and PRES offers intriguing support for the idea that vasoconstriction rather than vasodilation is the mechanism of vasogenic edema in PRES.
在加速性高血压中，与 PRES 相关的血管源性脑水肿可能代表自调节突破导致的血管扩张，也可能代表过度自调节导致的血管收缩。我们描述了 2 例加速性高血压合并 PRES 的患者出现浆液性视网膜脱离，这是一种血管收缩现象。浆液性视网膜脱离和 PRES 的同时出现，为这样一种观点提供了有趣的支持，即 PRES 中的血管源性水肿的机制是血管收缩而不是血管扩张。
