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[老年心脏:器官及其系统的衰老过程还是一个独立的临床实体?]

[Senile heart: an aging process of an organ and its system or an autonomous clinical entity?].

作者信息

Piermatteo E, Tizzano R, Femina G, Cirocco A, Policicchio D

机构信息

U.S.L. 4, Ospedale San Giacomo, Avellino Day Hospital Gerontologico.

出版信息

Clin Ter. 1990 Mar 31;132(6):367-78.

PMID:2139382
Abstract

Even though with increasing age it becomes progressively more difficult to distinguish between physiologic and pathologic changes and also considering the marked rise in the number of asymptomatic forms, the senile heart appears to be characterized by functional peculiarities rather than by specific organic alterations. Reduced contractility and myocardial compliance lead to the diminished effort adaptation characteristic for old age; to this must be added the degenerative changes of systemic vessels adding up to increased aortic impedance. Aging of the heart is not a clinical entity and therefore on no account requires therapeutic intervention provided investigation of each individual case has ascertained the absence of asymptomatic pathology. The sole possibility apt to delay the onset of overt pathology is physical exercise according to an individually tailored program.

摘要

尽管随着年龄的增长,区分生理变化和病理变化变得越来越困难,而且无症状形式的数量也显著增加,但老年心脏的特征似乎在于功能特性,而非特定的器质性改变。收缩力和心肌顺应性降低导致老年特有的努力适应能力下降;此外,全身血管的退行性变化导致主动脉阻抗增加。心脏衰老并非一种临床实体,因此,只要对每个个体病例的调查确定不存在无症状病理情况,就完全不需要进行治疗干预。唯一有可能延缓明显病理情况出现的方法是按照个性化定制的方案进行体育锻炼。

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