Chan J C, Hawkins B R, Cockram C S
Department of Medicine, Chinese University of Hong Kong.
Diabet Med. 1990 Mar-Apr;7(3):211-4. doi: 10.1111/j.1464-5491.1990.tb01372.x.
Non-insulin-dependent diabetes mellitus of early onset has recently been described in Caucasians as a distinct syndrome with a characteristic pedigree suggestive of inheritance of genetic determinants from both parents. It is characterized by absence of islet cell antibodies and the severity of its clinical course. We report a Chinese family pedigree of three generations in which this form of diabetes has affected the third generation. Some members of this pedigree had severe complications at presentation in their twenties.
早发性非胰岛素依赖型糖尿病最近在高加索人中被描述为一种独特的综合征,其特征性谱系提示遗传决定因素由父母双方遗传。它的特点是没有胰岛细胞抗体以及临床病程的严重程度。我们报告了一个三代中国家系,其中第三代受到了这种形式糖尿病的影响。这个家系的一些成员在二十多岁发病时就出现了严重并发症。