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由持续泛耐药的社区获得性金属β-内酰胺酶(IMP-1)阳性鲍曼不动杆菌引起的暴发性败血症。

Fulminating septicemia due to persistent pan-resistant community-acquired metallo-β-lactamase (IMP-1)-positive Acinetobacter baumannii.

作者信息

Telang Nilima V, Satpute Meenakshi G, Dhakephalkar Prashant K, Niphadkar Krishna B, Joshi Suresh G

机构信息

College of Medicine, Drexel University, Philadelphia, PA 19102, USA.

出版信息

Indian J Pathol Microbiol. 2011 Jan-Mar;54(1):180-2. doi: 10.4103/0377-4929.77397.

Abstract

Acinetobacter baumannii is considered as an emerging nosocomial pathogen and is renowned for its multi-drug resistance. We report a case of community-acquired pan-resistant A. baumannii caused fulminating septicemia. The treatment failure led to death. The A. baumannii strain isolated from blood, pus, urine and tracheal aspirate was confirmed by 16S r-RNA sequence homology and found positive for metallo-β-lactamase IMP-1, and was found to be a strong biofilm producer. The isolate was only susceptible (moderately) to colistin.

摘要

鲍曼不动杆菌被认为是一种新出现的医院病原体,以其多重耐药性而闻名。我们报告一例社区获得性泛耐药鲍曼不动杆菌引起的暴发性败血症病例。治疗失败导致死亡。从血液、脓液、尿液和气管吸出物中分离出的鲍曼不动杆菌菌株经16S r-RNA序列同源性确认,金属β-内酰胺酶IMP-1检测呈阳性,且发现该菌株是一种强大的生物膜产生菌。该分离株仅对黏菌素(中度)敏感。

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