Pan Tao, Liu Xiaoyun, Xiang Shougui, Ji Wenli
Department of Intensive Care Medicine, Xiangyang Hospital Affiliated to Hubei University of Medicine, Xiangyang, Hubei 441000, P.R. China.
Exp Ther Med. 2016 Apr;11(4):1345-1347. doi: 10.3892/etm.2016.3051. Epub 2016 Feb 8.
Bacterial infections are common but have become increasingly resistant to drugs. The aim of the present study was to examine the combined treatment of traditional Chinese and Western medicine in 30 cases of pulmonary infection with multidrug resistant . Patients were divided into groups A and B according to drug treatments. Cefoperazone or sulbactam and tanreqing were administered in group A, and cefoperazone or sulbactam in group B. The curative effect and prognosis of the two groups were recorded and the remaining treatments were performed routinely in the clinic. For the combined therapy group, which was administered sulperazone and tanreqing, 8 patients were recovered, 6 patients had significant effects, 3 patients exhibited some improvement and 1 patient had no response. One of the patients did not survive after 28 days. By contrast, there were 4 patients that were successfully treated, 3 patients with significant effects, 2 patients with some improvement and 2 patients had no response in the sulperazone group, and 4 patients did not survive after 28 days. In conclusion, the combined therapy of cefoperazone or sulbactam supplemented with tanreqing was identified to be more effective than cefoperazone or sulbactam as monotherapy, for treating multidrug resistant .
细菌感染很常见,但对药物的耐药性越来越强。本研究的目的是探讨中西医结合治疗30例多重耐药肺部感染的疗效。根据药物治疗方法将患者分为A组和B组。A组给予头孢哌酮或舒巴坦及痰热清,B组给予头孢哌酮或舒巴坦。记录两组的疗效和预后情况,其余治疗按临床常规进行。对于联合治疗组,即给予舒普深和痰热清的患者,8例康复,6例显效,3例有所改善,1例无反应。1例患者在28天后死亡。相比之下,舒普深组有4例患者成功治愈,3例显效,2例有所改善,2例无反应,4例患者在28天后死亡。总之,对于治疗多重耐药感染,头孢哌酮或舒巴坦联合痰热清治疗比单独使用头孢哌酮或舒巴坦更有效。