Department of Dermatology and STD, VM Medical College and Safdarjang Hospital, New Delhi, India.
Indian J Dermatol Venereol Leprol. 2011 Mar-Apr;77(2):222-31. doi: 10.4103/0378-6323.77478.
Sclerotherapy is defined as the targeted elimination of small vessels, varicose veins and vascular anomalies by the injection of a sclerosant. The aim of sclerotherapy is to damage the vessel wall and transform it into a fibrous cord that cannot be recanalized. It is a simple, cost-effective, efficacious and esthetically acceptable modality for both therapeutic and esthetic purposes.
Therapeutic indications include varicose veins and vascular malformations. Esthetic indications include telangiectasias and reticular veins. In the management of varicose veins, it may need to be combined with other surgical methods of treatment, such as ligation of the saphenofemoral junction, stab ligation of perforators and stripping. A surgical opinion may be necessary.
A thorough knowledge of the anatomy and physiology of the venous system of the legs, basic principles of venous insufficiency, methods of diagnosis and, in addition, uses, mechanisms of action and complications of sclerosing agents and proper compression techniques are important pre-requisites to successful sclerotherapy. Although various sclerosing agents are available, polidoconal and sodium tetradecyl sulfate are most commonly used. More recently, these sclerosants have been used in microfoam form for increased efficacy. The basic principle of a successful sclerotherapy technique is the use of an optimal volume and concentration of the sclerosant according to the size of the vessel. The sclerosant is injected carefully into the vessel and compression is applied.
Contraindications include superficial and deep venous thrombosis, sapheno-femoral junction incompetence, pregnancy, myocardial decompensation, migraine, hypercoagulable state, serious systemic illness, dependency edema, immobility, arterial disease, diabetes mellitus and allergic reactions to sclerosants.
While sclerotherapy is usually a safe procedure, complications may occur due to inappropriate patient selection or improper injection techniques. The complications may be acute or delayed. Complications include hyperpigmentation, matting, local urticaria, cutaneous necrosis, microthrombi, accidental intra-arterial injection, phlebitis, deep vein thrombosis, thromboembolism, scintillating scotomas, nerve damage and allergic reactions.
Sclerotherapy may be administered by a surgeon or dermatologist who has acquired adequate training during post-graduation or through recognized fellowships and workshops dedicated to sclerotherapy. He should have an adequate knowledge of the anatomy of the venous system, be able to diagnose and manage venous disease and its associated consequences as well as possess the necessary skills to perform the procedures, understand the appropriate indications and limitations, technique modifications and management of the potential adverse sequelae associated with sclerotherapy and also understand the pharmacology of the sclerosing solutions.
The procedure may be performed in the physician's procedure room.
硬化疗法是指通过注射硬化剂来靶向消除小血管、静脉曲张和血管畸形。硬化疗法的目的是破坏血管壁,使其转化为无法再通的纤维索。它是一种简单、具有成本效益、有效且美学上可接受的治疗方法,适用于治疗和美容目的。
治疗适应证包括静脉曲张和血管畸形。美容适应证包括毛细血管扩张和网状静脉。在静脉曲张的治疗中,可能需要与其他手术治疗方法相结合,如大隐静脉高位结扎、穿通支结扎和剥脱。可能需要外科医生的意见。
彻底了解腿部静脉系统的解剖和生理学、静脉功能不全的基本原理、诊断方法,此外还需要了解硬化剂的用途、作用机制和并发症以及适当的压缩技术,这些都是成功进行硬化疗法的重要前提。虽然有各种硬化剂可供选择,但聚多卡醇和十四烷基硫酸钠最常用。最近,这些硬化剂已以微泡形式用于提高疗效。成功的硬化疗法技术的基本原则是根据血管大小使用最佳体积和浓度的硬化剂。小心将硬化剂注入血管并施加压缩。
禁忌证包括浅静脉和深静脉血栓形成、大隐静脉高位结扎术失败、妊娠、心肌代偿失调、偏头痛、高凝状态、严重全身疾病、依赖性水肿、活动受限、动脉疾病、糖尿病和对硬化剂的过敏反应。
虽然硬化疗法通常是一种安全的程序,但由于选择不当的患者或不正确的注射技术,可能会出现并发症。并发症可能是急性的或延迟的。并发症包括色素沉着、哑光、局部荨麻疹、皮肤坏死、微血栓形成、意外动脉内注射、静脉炎、深静脉血栓形成、血栓栓塞、闪烁性暗点、神经损伤和过敏反应。
硬化疗法可由外科医生或皮肤科医生进行,他们在毕业后通过进修或参加专门的硬化疗法认可的奖学金和研讨会获得了足够的培训。他应该充分了解静脉系统的解剖结构,能够诊断和管理静脉疾病及其相关后果,并且具备执行手术的必要技能,了解适当的适应证和局限性、技术修改以及与硬化疗法相关的潜在不良后果的管理,并了解硬化剂的药理学。
该程序可以在医生的诊室中进行。