Shivhare Peeyush, Haidry Naqoosh, Sah Neha, Kumar Ajay, Gupta Abhishek, Singh Ankur, Penumatcha Mohan Raju, Subramanyam Shalini
Department of Dentistry, All India Institute of Medical Sciences, Patna 801507, India.
Department of Oral and Maxillofacial Surgery, Dental College Azamgarh, Azamgarh 276128, India.
Int J Dent. 2022 Sep 17;2022:8269221. doi: 10.1155/2022/8269221. eCollection 2022.
Pyogenic granuloma (PG) is a tumor-like, non-neoplastic lesion of the soft tissue that commonly appears in the oral cavity. Various treatment modalities have been discussed, including surgical excision, cryosurgery, curettage, electrodessication, corticosteroid injection, sclerotherapy, and lasers. This observational retrospective study compared effectiveness between diode lasers and sclerotherapy for PG treatment.
From July 2016 to January 2021, data of oral PG cases treated with sclerotherapy and diode lasers were gathered. Patients were evaluated and categorized according to their gender, sex, site of lesions, size of lesions, number of sessions, details of side effects, details of the VAS (Visual Analogue Scale) on third postoperative day, response of treatment to individual groups, time required for complete resolution, and details of recurrence. Inferential statistical analysis was performed.
We included 73 patients, of whom 43 and 30 received laser and sclerotherapy treatment, respectively. Compared with the sclerotherapy group, the laser group had less side effects including pain, edema, ulceration, ecchymosis, infections, and scarring. The difference in postoperative pain (VAS scale) between the groups was statistically significant (-value 0.004). Complete remission was seen in the laser group, while 3 cases of the sclerotherapy group had no response (-value -0.034). The laser group experienced greater recurrence than did the sclerotherapy group.
Both sclerotherapy with laser and 3% sodium tetradecyl sulfate are effective for treating oral PG. Sclerotherapy is more effective in preventing recurrence. In terms of side effects, diode lasers are superior to sclerotherapy.
化脓性肉芽肿（PG）是一种软组织的肿瘤样非肿瘤性病变，常见于口腔。已经讨论了多种治疗方式，包括手术切除、冷冻手术、刮除术、电干燥法、皮质类固醇注射、硬化疗法和激光治疗。这项观察性回顾性研究比较了二极管激光和硬化疗法治疗PG的效果。
收集2016年7月至2021年1月期间接受硬化疗法和二极管激光治疗的口腔PG病例数据。根据患者的性别、病变部位、病变大小、治疗次数、副作用细节、术后第三天视觉模拟量表（VAS）细节、各治疗组的治疗反应、完全消退所需时间以及复发细节进行评估和分类。进行了推断性统计分析。
我们纳入了73例患者，其中43例接受激光治疗，30例接受硬化疗法治疗。与硬化疗法组相比，激光组的副作用更少，包括疼痛、水肿、溃疡、瘀斑、感染和瘢痕形成。两组术后疼痛（VAS量表）差异具有统计学意义（P值0.004）。激光组实现了完全缓解，而硬化疗法组有3例无反应（P值0.034）。激光组的复发率高于硬化疗法组。
激光硬化疗法和3%十四烷基硫酸钠硬化疗法治疗口腔PG均有效。硬化疗法在预防复发方面更有效。在副作用方面，二极管激光优于硬化疗法。
