Riley L W, Castro Muñoz E, Zárate R J, Sibley B, Keller J, Zárate L G, Millán Velasco F, Schoolnik G K
Stanford University School of Medicine, California 94305.
Bol Oficina Sanit Panam. 1990 Feb;108(2):93-9.
A community-based, case-control study was conducted during the summer peak season for diarrhea in the highlands of Chiapas, Mexico, to identify risk and protective factors associated with acute diarrhea in children less than 6 years of age. To estimate the diarrheal morbidity rate, the community was divided into 13 sectors, each of about 20 households. A resident (volunteer mother) made daily visits to every household in her sector to identify new cases of diarrhea. During 3 weeks of surveillance, 63 children with diarrhea and 48 control children were identified. The diarrheal attack rate during this period for children less than 6 years of age was 30%. Analysis of 29 neighborhood-matched case-control pairs showed that children with diarrhea were more likely than their controls to have had a mother with diarrhea in the 2 weeks preceding the onset of the child's diarrhea (P less than 0.05; relative risk = 10). The association of childhood diarrhea with maternal diarrhea may serve as a focus for more detailed studies as well as an intervention that may be appropriate and effective for this community.
在墨西哥恰帕斯州高地腹泻高发的夏季，开展了一项基于社区的病例对照研究，以确定与6岁以下儿童急性腹泻相关的风险因素和保护因素。为估算腹泻发病率，该社区被划分为13个区，每个区约有20户家庭。一名居民（志愿母亲）每天走访所在区的每户家庭，以确定新的腹泻病例。在3周的监测期内，共确定了63例腹泻儿童和48例对照儿童。在此期间，6岁以下儿童的腹泻发病率为30%。对29对邻里匹配的病例对照进行分析发现，腹泻儿童在其腹泻发作前2周内，其母亲患腹泻的可能性高于对照儿童（P<0.05；相对风险=10）。儿童腹泻与母亲腹泻之间的关联，可作为更详细研究的重点，也可作为一项可能适用于该社区且有效的干预措施。
